Features of serum markers of myocardial fibrosis in the diagnosis of Wolf-Parkinson-White syndrome (WPW)

Most consider Wolff-Parkinson-White (WPW) syndrome to be an arrhythmia. However, the actual syndrome still remains a problem when choosing tactics for managing patients. Its significance is that this pathology affects people of young, working age. Ventricular preexcitation syndromes occur in all age groups and are verified in 1-30 patients per 10,000 people. However, in most cases, the clinical manifestation of the syndrome occurs between the ages of 10 and 20 years and is much less common in the elderly. The prevalence of preexcitation syndromes in the general population is approximately 0.15-0.25% and increases when combined with congenital heart defects - 0.5%. In 40-80% of patients, WPW syndrome is clinically manifested by various forms of cardiac arrhythmias (HRDs). Approximately half of these arrhythmias impair the quality of life and are often fatal [8]. The proportion of NRS with the participation of an additional path of atrioventricular conduction (AVS) reaches 54-75% of all supraventricular tachyarrhythmias (SVT), but without taking into account atrial fibrillation (AF).