Immunological disoders in patients with chronic renal insufficiency and possibility of immune therapy

The main evidence of the participation of immune responses in the pathogenesis of chronic renal failure (CRF) is an undoubted effect of treatment with corticosteroids, alkylating agents and cyclosporine A. This is supported by the relationship of nephrotic syndrome (NS) with atopy, Hodgkin's disease, certain HLA-types: DRw7, B12.This article presents a review of the literature, focused on the immunological changes in patients with impaired renal function, including сhroniс hemodialysis. Various aspects of immunocorrection in patients with chronic kidney disease are analyzed.