Studying the humoral components stimulating osteogenesis

Grebneva O.L.; Kovinka M.A.; Luneva S.N.; Larionova T.A.; Ovchinnikov E.N.; Samusenko D.V.; Гребнева Ольга Леонидовна; Ковинька Михаил Александрович; Лунева Светлана Николаевна; Ларионова Татьяна Адиславовна; Овчинников Евгений Николаевич; Самусенко Дмитрий Валерьевич

Scientific articles \ Applied sciences. Medicine. Technology \ Medical sciences \ Human biology \ Anatomy. Human and comparative anatomy

Studying the humoral components stimulating osteogenesis

Grebneva O.L. Kovinka M.A. Luneva S.N. Larionova T.A. Ovchinnikov E.N. Samusenko D.V.

Journal: Гений ортопедии @geniy-ortopedii

Section: Оригинальные статьи

Article in issue: 2, 2012.

Free access

The composition of the components of blood plasma osteogenic fraction was studied in patients after bone injury (the main group, n = 10), as well as that of similarly isolated blood serum fraction of somatically normal donors (the reference group, n = 10). The content of proteins, protein fractions, hydroxyproline, sialic and uronic acids, and also that of insulin-like growth factor-1 was studied. The fraction of the main group has been found to consist of polypeptide- and carbohydrate-origin components and to contain more than 20-fold higher concentration of insulin-like growth factor-1 in comparison with the reference group fraction.

osteogenesis \ blood plasma \ insulin-like growth factor 1

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