Echographic assessment of Wharton's jelly area in the predicting of fetal nondiabetic macrosomia

Objectives: The purpose of this study was to evaluate the effectiveness of Wharton’s jelly area as predictor of nondiabetic fetal macrosomia. Objectives of the study were to establish a correlation of Wharton’s jelly area with other fetal measurements and fetal weight and the use of this parameter for the early diagnosis of nondiabetic fetal macrosomia. Materials and methods: Fetal ultrasound examination was held in 179 pregnant women who had risk of fetal nondiabetic macrosomia and satisfied inclusion/exclusion criteria of the study. In addition to the standard fetal measurements cross-sectional Wharton’s jelly area was measured. Results and conclusion: It is established, that in most standard fetal measurements the significant differences between studied groups are absent. Cross-sectional Wharton’s jelly area index was higher in the study group and these differences are statistically significant, ranging from 15 weeks of gestation. Direct correlation square of Wharton’s jelly area with gestational age was identified in the group of fetal macrosomia as well in control group. By discriminant analysis the formula calculating the coefficient of the prediction of a large fetus was obtained, which is already 26 weeks gestation allows to determine of pregnant in the normosomia or macrosomia category with a high probability.