Clinical-biochemical substantiation of administration the “Yantovet” drug for cow ketosis

The aim of the studies was to evaluate the effect of an injectable preparation, including succinic acid and an organic phosphorus compound, on certain biochemical indexes of the blood of patients with subclinical cow ketosis. For this purpose, three groups of cows with ketosis were formed, with 10 heads in each group. The first group was injected the investigational medication intramuscularly three times with an interval of five days at the rate of 10 ml/animal, the second - 15 ml/animal, the third group was used as a control one. As a result of the analysis of the biochemical status of animals under the conditions of LLC “SetIle” “Novaya Sheshma” of the Republic of Tatarstan, at the first stage of the experiment the abnormalities were found in a number of parameters of carbohydrate, protein, lipid metabolism in cows that characterize subclinical ketosis. It was established that intramuscular administration of the test substance to the cows of experimental groups during the experiment led to a significant increase in blood glucose in the cows of experimental groups by 15-27% compared to the control group with a significant decrease in the total number of ketone bodies in the cows of experimental groups in 2-2.5 times. Positive changes were found in the quantitative expression of the milk productivity of experimental groups. Thus, the average daily yield of novice cows in experimental groups was 6-10% higher than in control group.