CT-semiotics of epimetaphyseal zones in patients with vitamin D-resistant rickets and in those with vitamin D-deficient rickets consequences after treatment by transosseous osteosynthesis method

Both structure and density of lower limb bones in 21 patients with vitamin D-resistant rickets and in those with vitamin D-deficient rickets consequences after treatment by transosseous osteosynthesis method were studied using computed tomography (CT) technique. The dynamics of structure changes in the femoral and tibial metaepiphyses of the patients with vitamin D-resistant rickets at the age of 11-16 years manifested itself in random arrangement of bone trabeculae in the medial parts, as well as in irregular sclerosis areas as compared to the bone structure of the patients with vitamin D-deficient rickets consequences. At the age of 17-23 years in the long-term period (from one to three years after the fixator removal), the greatest sclerotic changes were noted in the proximal tibial epiphysis (180±85 НU) while the least ones were in the distal femoral metaphysis (167±84 НU). At the age of 24-40 years, the patients with vitamin D-resistant rickets had minimal density values in the proximal tibial epiphysis (181±106 НU) that was associated with the degenerative changes, being extensive cyst-like reorganization at this level.