Молекулярно-генетические подходы в диагностике рака легких

Молекулярно-генетические подходы в диагностике рака легких

Автор: Ходырев Дмитрий Сергеевич, Никитин Алексей Георгиевич, Кулагина Наталья Сергеевна, Аверьянов Александр Вячеславович

Журнал: Клиническая практика @clinpractice

Рубрика: Обзоры

Статья в выпуске: 3-4 (23-24), 2015 года.

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В 21 веке остро стоит проблема поиска эффективных и дешевых методов для раннего выявления рака легких. Пациенты с подозрением на злокачественное заболевание легких, как правило, подвергаются клиническим исследованиям, таким как КТ-сканирование грудной клетки и бронхоскопия. Последнее преимущественно применяется для подтверждения диагноза. Тем не менее, даже когда признаки, симптомы и рентгенологические данные указывают на то, что клинический диагноз злокачественного заболевания легких является очевидным, требуются дополнительные инвазивные процедуры для получения биологического материала, пригодного для окончательного подтверждения наличия злокачественных клеток. В настоящее время есть четкое понимание необходимости поиска биомаркеров, способных на доклинической стадии выявлять клетки рака с помощью малоинвазивных процедур.

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Рак легких, биомаркеры, днк метилирование, микрорнк

Короткий адрес: https://sciup.org/14338537

IDR: 14338537

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