Obtaining a probiotic consortium based on strains isolated from cow's milk

For the prevention and normalization of the microbiota, the imbalance of which leads to a violation of the healthy state of the body, the use of probiotics is promising, and therefore, their development. This work is aimed at creating a probiotic consortium. In the course of the study, the strains of L. acidophilus, L. plantarum and L. casei were isolated, on the basis of which various consortia were assembled. The results showed that a consortium consisting of L. plantarum, L. casei, L. acidophilus in a ratio of 3:1:1, had the maximum accumulation of cell biomass for a specified time, showed antibiotic activity against a number of pathogenic and opportunistic strains, resistance to the action of antibiotics and to the unfavorable conditions of the gastrointestinal tract. In order to use the consortium as a probiotic and use it in the food industry, it is planned to study the nature and activity of its cellular metabolites, and study its technological properties in the future.