Early unlearning process from artificial lung ventilation use as a factor in the prevention of bronchopulmonary dysplasia

Bronchopulmonary dysplasia has a multifactorial etiology, which includes prolonged use of artificial lung ventilation. Therefore, it is desirable to unlearn premature infants from invasive ventilation as soon as possible. However, it is equally important to avoid premature and/or unprepared unlearning, as this can lead to increased breathing, acute health deterioration, and the need for reintubation, which can have a catastrophic impact on neonatal outcomes. The three main tasks can be identified, when unlearning from artificial lung ventilation use: pharmacological preparation for unlearning process, strategies for artificial lung ventilation use during the unlearning process, and methods of respiratory support after extubation. Identifying factors associated with successful extubation can help reduce the duration of artificial lung ventilation use, and assist in the development of future research to improve outcomes of artificial lung ventilation in premature infants.