Recipe, production technology and commodity characteristics of the biologically active additive “Neurostabil”

A recipe formula for the new type of biologically active additive (BAA) "Neurostabil" has been developed taking into account the pharmacological characteristics of the active principles of the initial ingredients and their synergistic properties with respect to the correction of metabolic processes. Along with local plant raw materials the recipe includes vitamin preparations (retinol, tocopherol, riboflavin, thiamine, pyridoxine, niacinamide, calcium pantothenate, cyanocobalamine, folic and ascorbic acids), minerals and vitamin premix. An innovative tabletting technology for a specialized product has been proposed and tested. Moderate technological parameters of production: granulate drying at (65 ± 5) °C to 5-7 % of residual moisture and other processes at room temperature provide stability of consumer and functional properties. Regulated quality indicators, including nutritional values, terms and modes of storage have been determined: 3 years in a dry, protected from light place, at a temperature not higher than 25 °C. The efficacy of BAA is confirmed by conducting clinical testing in representative groups of patients with peptic ulcer of the stomach, duodenum in combination with hypertension. The parameters of the acid-forming function, the dynamics of the endoscopic and morphological picture of the stomach, the number of nucleic acids in duodenal and gastric aspirates, as well as the indices of psychosomatic disorders, clinical manifestations before and after complex diet therapy have been studied. The ability of a specialized product to reduce the symptoms of peptic ulcer of the stomach and duodenum, positively influence the epithelization of erosion of the stomach, reduce inflammation and the manifestation of gastritis is demonstrated. Improvement of the psycho-emotional state of patients is noted. The developed product is tested and produced at the enterprises of R&D “Art Life”, (Tomsk).