Состояние метаболических процессов и фагоцитарной системы крыс в экспериментальной модели

A necessary link in various adaptive reactions of the organism is stress, which relies on nonspecific reactions of the organism, reflecting the state of tension of the functions of organs and systems and ensuring the mobilization of its reserve capabilities. The literature still lacks relevant information about the long-term effects of low doses of radiation in the case of natural radiation, radioactive fallout after testing atomic bombs or nuclear power plant emissions. For this purpose, experimental studies were conducted on rats. The organism of pregnant animals can be affected by various environmental factors, but in this case, the leading is ionizing radiation, in order to find out whether the resulting changes are due to radiation, we reproduced our experience in an experimental model. As a result, it was found out that the increase the level of cholesterol, total lipids, decreases the amount of CIC, sugar and total protein. The rat phagocytic system also undergoes significant changes, which are manifested in an increase in adolescent and band neutrophils, which indicates a shift of the nucleus to the left and the inability to perform its functions by microphages, due to its immaturity. An increase in the NBT test and a decrease in LKT indicate a violation of the constancy of the internal environment and a decrease in the body's reactivity, which coincides with the literature data.