A comparative study of the formation of DNA double-strand breaks in the cells of the PC3 line (human prostate cancer) under exposure to gamma radiation with ultra-high and therapeutic dose rate
Автор: Shishkin A.M., Kulinich T.M., Krastelev E.G., Bykov Y.A., Smirnov V.P., Ivanov A.V., Vassiliev V.N., Bojenko V.K.
Журнал: Вестник Российского научного центра рентгенорадиологии Минздрава России @vestnik-rncrr
Рубрика: Молекулярная медицина
Статья в выпуске: 3 т.18, 2018 года.
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Summary We conducted a comparative study of the effects of therapeutic gamma radiation and x-ray radiation with an ultra-high dose rate of the experimental setup "MIR-M" in human prostate cancer cells line PC3. The assessment of the level of double-strand breaks (DSBs) of DNA was performed. In comparison with therapeutic radiation, ultra-high dose rate radiation, at equal equivalent doses of radiation, caused remarkably more DSBs and the differences by the number of DSDs increased with increasing radiation dose.
Рак предстательной железы pc3
Короткий адрес: https://sciup.org/149132069
IDR: 149132069
