Effect of furazolidone on white blood cell indices of chickens

Antibacterial drugs in the poultry farming system are used for the prevention and treatment of infectious pathology. With the intensive introduction of a pharmacological drug into production, it is necessary to establish the possible presence and nature of the negative impact of such a drug on physiological state of poultry. A serious advantage of nitrofurans is the difficulty of developing resistance in a wide range of microorganisms to drugs of this group. The purpose of the study is to study the morphofunctional parameters of chicken blood when using furazolidone. Analysis of hematological blood parameters indicates the absence of a negative effect of furazolidone on the physiological state of chickens when drinking in the first ten days of life at a dose of 200 mg/l, compared with similar indicators in the intact control group. The studied indices of white blood cells characterize the absence of a negative effect of the studied preparation on the state of the immune system of chickens. The use of furazolidone does not lead to the development of intoxication and occurrence of inflammatory processes in the body of animals of the experimental group. When analyzing the leukogram data, granulocytosis was established in birds of the experimental group, accompanied by minor pseudo-eosinophilia. The calculation of leukocyte indices indicates insignificant differences from those in the intact control group. At the same time, hematological indices were within the normative values. There were no statistically significant differences between leukogram indices in the intact control and experimental groups by the ninth day after drug withdrawal. The leukogram values of the experimental group chickens were equal to the control values by the ninth day after the drug was discontinued, which indicates the absence of a critical effect of furazolidone on the body.