Effect of probiotic preparations on mineral metabolism indicators of geese

Scientific and practical research on the effect of Vetom-1 and Vetom-2 drugs on mineral metabolism indicators of geese were conducted at Research and Production Firm “Research Center” LLC in Koltsovo of Novosibirsk region and at the laboratory of Pharmacology and General Pathology Department of Veterinary Medicine Faculty of Novosibirsk State Agricultural University. Biochemical parameters in the geese’s blood serum were measured using an open-type iMagic-V7 biochemical analyzer (veterinary version), manufactured by Shenzhen iCubio Biomedical Technology Co., Ltd. Geese were divided into seven experimental groups and one control group (10 birds per group). The experimental groups received medications with compound feed at doses of 50 and 75 mg/kg according to different schedules for 15, 30, or 90 days. After application, blood samples were taken from geese in all experimental groups for biochemical analysis. To determine intergroup differences, Kruskal-Wallis test was used as an alternative nonparametric analogue of Fisher exact test, within the framework of a one-way analysis of variance when comparing three or more independent groups. Calcium, chlorides and serum iron were determined in blood serum. The medications did not significantly affect calcium levels (the concentration after administration remained within the physiological norm). Chloride levels were reduced after administration; on the 90th day of the experiment, chloride levels in experimental groups No. 2, 5, and 7 decreased by 8-10.2% compared to the control group. Serum iron concentrations in experimental groups 1, 3, 5, and 7 decreased compared to the control group. The greatest effect of the drug was observed with long-term use (90 days). The drugs at the indicated doses did not have a toxic effect.