Diagnostic possibilities of bone scintigraphy in osteoporotic vertebral changes and assessment of bone remodeling in patients with osteoporosis

Purpose: to assess the role of bone scintigraphy in the diagnosis of osteoporotic changes of the vertebral bodies and the reparative processes in the vertebrae. Materials and methods. We examined 114 patients with T - test less than -1.0 (according to DXA). We performed bone scan, X-ray examination, tests for serum osteocalcin, parathyroid hormone, bone alkaline phosphatase. The analysis of the correlations between bone scan, x-ray measurements and clinical and laboratory parameters was carried out. Mathematical modeling of the structural - functional reconstruction of bone tissue in osteoporotic changes in the vertebral bodies was performed. Results. We found correlations between the data of bone scan, X-ray measurements and clinical and laboratory parameters. The diagnostic role of accumulation of osteotropic indicator based on ROC-analysis in the diagnosis of osteoporotic vertebral fractures was demonstrated. Conclusions. We demonstrated the role of bone scintigraphy in the diagnosis of osteoporotic vertebral fractures.