Исследования первых антиагрегантов: ацетилсалициловая кислота, тиклопидин и клопидогрел

Исследования первых антиагрегантов: ацетилсалициловая кислота, тиклопидин и клопидогрел

Автор: Гительзон Д.Г., Файбушевич А.Г., Гительзон Е.А., Денека А.Я., Васильев А.Э., Данишян К.И.

Журнал: Вестник Национального медико-хирургического центра им. Н.И. Пирогова @vestnik-pirogov-center

Рубрика: Обзоры литературы

Статья в выпуске: 4-2 т.17, 2022 года.

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Антиагреганты значительно снизили смертность и заболеваемость ИБС, нарушениями мозгового кровообращения, артериальной недостаточностью нижних конечностей. Поэтому антиагреганты являются важной частью оптимальной медикаментозной терапии у таких пациентов. Ацетилсалициловая кислота остается наиболее часто рекомендованным лекарственным препаратом, особенно для профилактики тромботических осложнений. Клопидогрел является альтернативой ацетилсалициловой кислоте, а также важным компонентом двойной антитромботической терапии при баллонной ангиопластике и стентировании. Тиклопидин не используется в практике согласно клиническим рекомендациям из-за многочисленных побочных эффектов и разработки более безопасных и эффективных антагонистов P2Y12 рецепторов.

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Антиагреганты, ацетилсалициловая кислота, тиклопидин, клопидогрел

Короткий адрес: https://sciup.org/140300775

IDR: 140300775   |   DOI: 10.25881/20728255_2022_17_4_2_121

Список литературы Исследования первых антиагрегантов: ацетилсалициловая кислота, тиклопидин и клопидогрел

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