Нехирургические методы лечения болезни Пейрони
Автор: Красняк Степан Сергеевич
Журнал: Экспериментальная и клиническая урология @ecuro
Рубрика: Эндоурология
Статья в выпуске: 3, 2020 года.
Бесплатный доступ
Введение. По различным оценкам болезнь Пейрони (БП) поражает приблизительно 3-9% мужчин во всем мире и может проявляться болью, эректильной дисфункцией и деформацией полового члена, включая его укорочение. Это состояние оказывает значительное негативное влияние на качество жизни, самооценку и психологическое благополучие. Цель. Изучить опубликованные на май 2020 года данные по наиболее эффективным и безопасным методам медикаментозного и иного нехирургического лечения болезни Пейрони. Материалы и методы. Были проанализированы результаты поиска по научным базам данных PubMed, MEDLINE, Embase по запросам «болезнь Пейрони», «медикаментозное лечение», «нехирургическое лечение», «инъекционная терапия». Было найдено 2532 научные публикации, после исключения дубликатов, литературных обзоров, материалов конференции для детального анализа отобрано 74 работы, включенные в настоящий обзор. Результаты. Нехирургическое лечение, включая пероральную, тракционную, ударно-волновую и локальную инъекционную терапии, может позволить пациентам избежать осложнений, связанных с хирургическим вмешательством, и достичь улучшенных функциональных и эстетических результатов. В настоящее время при лечении БП используются несколько вариантов нехирургического лечения, которые могут уменьшить или стабилизировать как объективные показатели (например, длину и деформацию полового члена), так и субъективные показатели (включая сексуальную функцию, боль и удовлетворенность партнера). Выводы. Пероральная терапия может включать в себя пара-аминобензойную кислоту, D-а-токоферол и L-карнитин, в качестве инъекционной терапии могут быть рекомендованы верапамил, клостридиальная коллагеназа. Экстракорпоральная ударно-волновая терапия может быть использована в Российской Федерации в рамках клинических исследований.
Болезнь пейрони, парааминобензойная кислота, тракционная терапия, пероральная терапия
Короткий адрес: https://sciup.org/142225705
IDR: 142225705 | DOI: 10.29188/2222-8543-2020-12-3-95-102
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