Development of technology for collecting and harvesting the herb of Linum pallescens and Linum heterosepalum

Development of an optimal technology for the collection and harvesting of Linum pallescens Bunge. and Linum heterosepalum Regel. herb is aimed at ensuring the preservation of biological activity, raw material quality, high technological efficiency and environmental sustainability of the processes. The implementation of the “Quality by Design” (QbD) concept in the development of technological processes makes it possible to systematically account for risks influencing critical quality attributes and to establish conditions for their optimization. The aim of the present study is to develop an optimal technology for the collection and harvesting of Linum pallescens and Linum heterosepalum herb to ensure quality based on the QbD concept. The plant specimens were identified by employees of the RSE REM «Institute of Botany and Phytointroduction». Within the framework of the QbD concept, statistical analysis with Minitab software was performed to establish the design space for the drying and harvesting processes of plant raw materials from both Linum species. The integration of the QbD concept into the process of developing the technology for the collection and harvesting of Linum pallescens and Linum heterosepalum herb demonstrated high efficiency. The results confirm the potential of applying QbD to improve quality, efficiency and control at all stages of medicinal plant raw material harvesting.