Закономерности развития рестеноза после стентирования окклюзирующих и неокклюзирующих поражений коронарных артерий

1928 patients with implanted stents were examined for the purpose of identifying the regularity of restenosis development after stenting occluding and nonoccluding lesions of coronary arteries (CA). After six months check coronary angiography was per-formed for 1276 patients with 274 occlusions and 1442 stenoses of CA. To carry out a comparative analysis of the study results, a computer algorithm of selecting pairs of cases with CA occlusions and stenoses was developed, which took into account a patient's age, presence of diabetes, affected vessel, lesion type (primary one or restenosis), as well as types of stents used. In the course of studying no significant difference was disclosed in the occurrence of restenoses for the groups with occluding and non-occluding lesions (33% и 28% respectively)) and in the occurrence of reocclusion development ((4.8% и 2.7% respectively). Neither was there any significant difference in the measures of a late lumen loss factor. The impact of CA lesions (occlusion, stenosis) on the restenosis development is not of critical importance, and when removing other morpho-anatomic causes contributing to restenosis, the degree of neointima hyperplasia, as a major component of restenosing when stenting, does not differ in patients with occluding and nonoccluding lesions of CA.