Изготовление микрофлюидного чипа с использованием технологий FDM- и LCD-печати для получения гидрогелевых альгинатных микросфер

Fabrication of a microfluidic chip via fdm and lcd printing for alginate hydrogel microspheres production

Despite their great potential in research practice, microfluidic systems are not more widely adopted due to the high cost of producing key components, particularly microfluidic chips (MFCs). For this reason, there is active research into new MFC prototyping methods. Over the past decade, there has been an increasing trend towards using 3D printing technologies for this purpose. This paper discusses the possibility of using MFCs to generate single monodisperse emulsions. The MFC is designed as a system that integrates components created using fused deposition modelling (FDM) and LCD printing technology with readily available elements, such as medical needles and glass capillaries. The assembled MFCs were used as part of a setup for synthesis calcium alginate-based hydrogel particles. Using this setup, highly uniform microspheres were produced.