The effectiveness of experimental herbal medicine for atherosclerosis with saponins

Автор: Don A.N., Kakharov Z.A., Hwang O.I.

Статья в выпуске: 1 (21), 2024 года.

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Статья посвящена вопросам фитотерапии атеросклероза тритерпеновыми сапонинами. Профилактика и лечение болезней растительными лекарствами известно с древних времен. Главным преимуществом является возможность их применения для профилактики и лечения атеросклероза и связанных с ним сердечно-сосудистых заболеваний. Общепринятым считается, что профилактика позволяет предотвратить и/или отсрочить сердечно-сосудистые заболевания. Но удается это не всегда, поэтому внимание исследователей привлекают препараты растительного происхождения. Общеизвестными считаются их преимущества, в сравнении с синтетическими препаратами. Экспериментальный атеросклероз был моделирован на кроликах. Фитотерапия представлена изучением растительных тритерпеновых сапонинов: леонтозид, дипсакозид и ладыгинозид. Выявлено, что наиболее высоким эффектом на атеросклероз кроликов показал ладыгинозид, который в сравнении с животными холестеринового контроля, приводит к снижению атерогенных поражений в 3,77 раз. Следующим идет дипсакозид, снизивший поражение атеросклерозом в 3,70 раза. Третье место занимает леонтозид, который уменьшил атерогенные поражения в 3,22 раза.

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Экспериментальный атеросклероз, ладыгинозид, дипсакозид, леонтозид, тритерпеновые, гликозиды

Короткий адрес: https://sciup.org/14130728

IDR: 14130728

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