Ways of regulation of release of medicinal substances from the chitosan films
Автор: Kulish Elena Ivanovna, Shurshina Anzhela Samatovna, Pearce Eli M.
Журнал: НБИ технологии @nbi-technologies
Рубрика: Технико-технологические инновации
Статья в выпуске: 1 (10), 2014 года.
Бесплатный доступ
The article studies the chitosan films obtained by applying acetic acid and two antibiotics of cephalosporin and aminoglycoside type. It investigates the possibility of their transport properties regulation in the sphere of medicines manufacture. This regulation can be carried out by films with thermal modification implying the heating of formed films at the temperature of about 120 °C and reaction with sodium dodecyl sulphate. The article shows that the antibiotics release from films will be determined by the amount of antibiotics connected with chitosan by hydrogen bonds, on the one hand, and by the state of the polymer matrix, on the other hand.
Chitosan, modification, medicines manufacture, polymer matrix, films
Короткий адрес: https://sciup.org/14968305
IDR: 14968305
Список литературы Ways of regulation of release of medicinal substances from the chitosan films
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