Источники происхождения серозных карцином яичника высокой степени злокачественности

Автор: Асатурова А.В.

Журнал: Злокачественные опухоли @malignanttumors

Статья в выпуске: 3S1 т.9, 2019 года.

Бесплатный доступ

Карциномы яичников - одно из ведущих заболеваний среди причин смертности женщин по всему миру. Ранняя диагностика данных опухолей затруднена в первую очередь из-за неопределенности в отношении источника их возникновения. В настоящее время двумя основными конкурирующими теориями происхождения серозных карцином яичника высокой степени злокачественности являются теории, рассматривающие в качестве источника развития этих опухолей поверхностный эпителий яичника и эпителий маточной трубы. В данной статье приведены доказательства обоснованности обеих теорий. Приводится обоснование выделения переходных зон между фимбриальным отделом маточной трубы, мезотелием брюшины и поверхностным эпителием яичника в качестве альтернативного источника происхождения серозных карцином яичника высокой степени злокачественности. Теория переходных зон, имеющих общее эмбриональное развитие, может стать объединяющей, нивелирующей недостатки каждой из ныне существующих.

Еще

Серозная карцинома яичника, маточная труба, поверхностный эпителий яичника, переходная зона

Короткий адрес: https://sciup.org/140249264

IDR: 140249264 | DOI: 10.18027/2224-5057-2019-9-3s1-9-14

Список литературы Источники происхождения серозных карцином яичника высокой степени злокачественности

Auersperg N., Wong A.S., Choi K.C., Kang S.K., Leung P.C. Ovarian surface epithelium: biology, endocrinology, and pathology // Endocr. Rev. 2001;22:255- 88.
Auersperg N. Ovarian surface epithelium as a source of ovarian cancers: Unwarranted speculation or evidence-based hypothesis? // Gynecol Oncol. 2013; 130 (1):246-51.
Auersperg N. The origin of ovarian cancers - hypotheses and controversies // FrontBiosci (Schol Ed). 2013;5:709-19.
Auersperg N. The stem-cell profile of ovarian surface epithelium is reproduced in the oviductal fimbriae, with increased stem-cell marker density in distal parts of the fimbriae // Int. J. Gynecol. Pathol. 2013;32 (5):444.
Bowen N.J., Walker L.D., Matyunina L.V., Logani S., Totten K. A., Benigno B. B. et. al. Geneexpression proﬁling supports the hypothesis that human ovarian surface epithelia are multipotent and capable of serving as ovarian cancer initiating cells // BMCMed Genomics. 2009;29 (2):71.
Callahan M.J., Crum C.P., Medeiros F., Kindelberger D.W., Elvin J. A., Garber J.E. et al. Primary fallopian tube malignancies in BRCA-positive women undergoing surgery for ovarian cancer risk reduction // J. Clin. Oncol. 2007;1 (25):3985-90.
Carcangiu M.L., Peissel B., Pasini B., Spatti G., Radice P., Manoukian S. Incidental carcinomas in prophylactic specimens in BRCA1 and BRCA2 germ-line mutation carriers, with emphasis on fallopian tube lesions: report of 6 cases and review of the literature // Am. J. Surg. Pathol. 2006;30 (10):1222-30.
Carlson J.W., Miron A., Jarboe E.A., Parast M.M., Hirsch M.S., Lee Y. et al. Serous tubal intraepithelial carcinoma: its potential role in primary peritoneal serous carcinoma and serous cancer prevention // J. Clin. Oncol. 2008, 26:4160 -5.
Connolly D.C., Bao R., Nikitin A.Y., Stephens K.C., Poole T.W., Hua X. et al. Female mice chimeric for expression of the simian virus 40TAg under control of theMISIIR promoter develop epithelial ovarian cancer // Cancer Res. 2003;15: 1389-97.
Crum C.P., Drapkin R., Kindelberger D., Medeiros F., Miron A., Lee Y. Lessons from BRCA: The Tubal Fimbria Emerges as an Origin for Pelvic Serous Cancer // Clin. Med. Res.2007;5 (1):35- 44.
Finch A., Shaw P., Rosen B., Murphy J., Narod S.A., Colgan T.J. Clinical and pathologic findings of prophylactic salpingo-oophorectomies in 159 BRCA1 and BRCA2 carriers // Gynecol. Oncol. 2006;100:58- 64.
Flesken-Nikitin A., Choi K.C., Eng J.P., Shmidt E.N., Nikitin A.Y. Induction of carcinogenesis by concurrent inactivation of p53 and Rb1 in the mouse ovarian surface epithelium // Cancer Res. 2003;63:3459- 63.
Flesken- Nikitin A., Hwang C. I., Cheng C.Y., Michurina T.V., Enikolopov G., Nikitin A.Y. Ovarian surface epithelium at the junction area contains a cancer-prone stemcell niche // Nature 2013;495:241-5.
Gamwell L.F., Collins O., Vanderhyden B.C. The mouse ovarian surface epithelium contains a population of LY6A (SCA-1) expressing progenitor cells that are regulated by ovulation- associated factors // Biol. Reprod. 2012;4 (87):80.
Jazaeri A. A., Bryant J. L., Park H., Li H., Dahiya N., Stoler M.H. et al. Molecular Requirements for Transformation of Fallopian Tube Epithelial Cells into Serous Carcinoma // Neoplasia. 2011;13 (10):899-911.
Kindelberger D.W., Lee Y., Miron A., Hirsch M.S., Feltmate C., Medeiros F. et al. Intraepithelial carcinoma of the fimbria and pelvic serous carcinoma: evidence for a causal relationshi // Am. J. Surg. Pathol. 2007;31:161-9.
King S.M., Quartuccio S.M., Vanderhyden B.C., Burdette J.E. Early transformative changes in normal ovarian surface epithelium induced by oxidative stress require Akt upregulation, DNA damage and epithelial - stromal interaction // Carcinogenesis. 2013;34 (5):1125-33.
Kobayashi A., Shawlot W., Kania A., Behringer R.R. Requirement of Lim1 for female reproductive tract Development // Development 2004;131:539- 49.
Kuhn E., Kurman R.J., Vang R,. Sehdev A.S., Han G., Soslow R. et al. Tp53 mutations in serous tubal intraepithelial carcinoma and concurrent pelvic high-grade serous carcinoma - evidence supporting the clonal relationship of the two lesions // J. Pathol. 2012;226 (3):421- 6.
Kuhn E., Meeker A., Wang T.L., Sehdev A.S., Kurman R.J., Shih I. Shortened telomeres in serous tubal intraepithelial carcinoma: an early event in ovarian high-grade serous carcinogenesis // J Pathol. 2012;226 (3):421- 6.
Kurman R.J., Shih Ie-M. Molecular Pathogenesis and Extraovarian Origin of Epithelial Ovarian Cancer. Shifting the Paradigm // Hum. Pathol. 2011;42 (7):918-31.
Lamb J.D., Garcia R.L., Goff B.A., Paley P.J., Swisher E.M. Predictors of occult neoplasia in women undergoing risk-reducing salpingo- oophorectomy // Am. J. Obstet. Gynecol. 2006;194 (6):1702-9.
Lee Y., Miron A., Drapkin R., Nucci M.R., Medeiros F., Saleemuddin A. et al. A candidate precursor to serous carcinoma that originates in the distal fallopian tube // J Pathol. 2007;211:26-35.
Li J., Fadare O., Xiang L., Kong B., Zheng W. Ovarian serous carcinoma: recent concepts on its origin and carcinogenesis // J. Hematol. Oncol. 2012;9:5- 8.
Marquez R.T., Baggerly K. A., Patterson A. P. Liu J., Broaddus R., Frumovitz M. et al. Patterns of gene expression in different histotypes of epithelial ovarian cancer correlate with those in normal fallopian tube, endometrium, and colon // Clin. Cancer Res. 2005;11 (17):6116-26.
Medeiros F., Muto M.G., Lee Y., Elvin J.A., Callahan M.J., Feltmate C. et al. The tubal fimbria is a preferred site for early adenocarcinoma in women with familial ovarian cancer syndrome // Am. J. Surg. Pathol. 2006;30:230 - 6.
Okamura H., Katabuchi H. Detailed morphology of human ovarian surface epithelium focusing on its metaplastic and neoplastic capability // Ital. J. Anat. Embryol. 2001;106 (Suppl. 2):263-76.
Ozcan A., Truong L.D. PAX2 and PAX8 expression in the ovarian surface epithelium and inclusion cysts // Am. J. Surg. Pathol. 2012;36 (7):1100 -10102.
Piek J.M. van Diest P.J., Zweemer R.P., Jansen J.W., Poort-Keesom R.J., Menko F.H. et al. Dysplastic changes in prophylactically removed Fallopian tubes of women predisposed to developing ovarian cancer // J. Pathol. 2001;195 (4): 451- 6.
Pothuri B., Leitao M.M., Levine D.A., Viale A., Olshen A.B., Arroyo C. et al. Genetic analysis of the early natural history of epithelial ovarian carcinoma // PLoS One 2010;5 (4):e10358.
Powell C. B., Kenley E., Chen L. M., Crawford B., McLennan J., Zaloudek C. et al.: Risk-reducing salpingo-oophorectomy in BRCA mutation carriers: role of serial sectioning in the detection of occult malignancy // J. Clin. Oncol. 2005; 23 (1):127-32.
Przybycin C.G., Kurman R.J., Ronnett B.M., Shih I., Vang R. Are all pelvic (nonuterine) serous carcinomas of tubal origin? // Am. J. Surg. Pathol. 2010;34 (10):1407-16.
Roh M.H., Kindelberger D., Crum C.P. Serous tubal intraepithelial carcinoma and the dominant ovarian mass: clues to serous tumor origin? // Am. J. Surg. Pathol. 2009;33 (3):376- 83.
Sajjad Y. Development of the genital ducts and external genitalia in the early human embryo // J. Obstet. Gynaecol. Res. 2010;36 (5):929-37.
Salamanca C.M., Maines-Bandiera S.L., Leung P.C., Auersperg N. Effects of epidermal growth factor/ hydrocortisone on the growth and differentiation of human ovarian surface epithelium // J. Soc. Gynecol. Investig. 2004;11 (4):241-51.
Salvador S., Rempel A., Soslow R.A., Gilks B., Huntsman D., Miller D. Chromosomal instability in fallopian tube precursor lesions of serous carcinoma and frequent monoclonality of synchronous ovarian and fallopian tube mucosal serous carcinoma // Gynecol. Oncol. 2008;110 (3) 6:408- 417.
Sarraj M. A., Drummond A. E. Mammalian foetal ovarian development: consequences for health and disease // Reproduction. 2012;143 (2):151- 63.
Schauer I.G., Sood A. K., Mok S., Liu J.Cancer- associated ﬁbroblasts and their putative role in potentiating the initiation and development of epithelial ovarian cancer //Neoplasia 2011;13 (5):393- 405.
Scully R.E. Pathology of ovarian cancer precursors // J. Cell Biochem. Suppl. 1995;23:208-18.
Seidman J.D. Serous tubal intraepithelial carcinoma localizes to the tubal-peritoneal junction: a pivotal clue to the site of origin of extrauterine high-grade serous carcinoma (ovarian cancer) // Int. J. Gynecol. Pathol. 2015;34 (2):112-20.
Sherman-Baust C.A., Kuhn E., Valle B.L., Shih Ie.M., Kurman R.J. et al. A genetically engineered ovarian cancer mouse model based on fallopian tube transformation mimics human high-grade serous carcinoma development // J. Pathol. 2014;233 (3):228-37.
Szotek P.P., Chang L.H., Brennand K., Fujino A., Pieretti-Vanmarcke R, et al. Normalovarian surface epithelial label-retaining cells exhibit stem / progenitor cell characteristics // Proc. Natl. Acad. Sci.2008;26 (105):12469-73.
Tone A.A., Begley H., Sharma M. Murphy J, Rosen B., Brown T.J. et al. Gene expression proﬁles of luteal phase fallopian tube epithelium from BRCA mutation carriers resemble high-grade serous carcinoma // Clin. Cancer Res. 2008;14 (13): 4067-78.
Vang R., Shih Ie.M., Kurman R.J. Fallopian tube precursors of ovarian low- and high-grade serous neoplasms // Histopathology. 2013;62 (1):44-58.
Zheng W., Fadare O. Fallopian tube as main source for ovarian and pelvic (non-endometrial) serous carcinomas // Int. J. Clin. Exp. Pathol. 2012;5 (3):182- 6.

Еще

Статья научная