Morpho-functional factors of stomach cancer prognosis
Автор: Ablakimov K.N.
Журнал: Экономика и социум @ekonomika-socium
Рубрика: Основной раздел
Статья в выпуске: 12-1 (91), 2021 года.
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Gastric cancer (RV) is a heterogeneous group of carcinomas with a high malignant potential and an unfavorable prognosis. Obviously, there are a number of issues in the study of RS that require further in-depth research. There is no comprehensive data on the effect of the regularities of cell renewal of carcinoma and the functional immunophenotype of tumor cells on the malignant potential of RV. The prognostic significance of the expression of intercellular and cell-matrix adhesion molecules (E-cadherin (E-SUB), type 4 collagen (CO4)), extracellular matrix proteins and proteases (ECM) remains debatable; tenascin-C (TC-C), matrix metalloproteinases of type 2 and 3 (MMR2 and MMRZ)), as well as the regulatory protein galectin-3 (VAZ), including in various IFT variants of RV. A generally accepted algorithm for the individual prognosis of carcinomas of this localization has not been developed, taking into account the key molecular biological factors of the malignant potential of the tumor.
Stomach cancer, morphofunctional and morphobiological characteristics
Короткий адрес: https://sciup.org/140262441
IDR: 140262441
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