Патоморфология субмакулярного кровоизлияния (обзор)

Автор: Файзрахманов P.P., Шишкин М.М., Босов Э.Д., Суханова А.В., Миронов А.В.

Журнал: Саратовский научно-медицинский журнал @ssmj

Статья в выпуске: 1 т.17, 2021 года.

Бесплатный доступ

Субмакулярное кровоизлияние является серьезным осложнением различных заболеваний глаз, приводящим к стойкой и нередко необратимой потере зрения. Одной из основных причин данной патологии является возрастная макулярная дегенерация (ВМД). Сформировавшееся кровоизлияние оказывает выраженные деструктивные изменения в фоторецепторном и наружном ядерном слоях сетчатки. Патоморфологические нарушения опосредованы комплексным влиянием нейротоксических продуктов распада крови, тракционного воздействия фибриновых нитей, а также блокирование метаболических процессов между ретинальным пигментным эпителием и вышележащими слоями сетчатки. Обзор литературы проведен с использованием поисковых систем PubMed, Embase, Cochrane Library, выполнен анализ источников литературы по заданной теме, опубликованных с 1959 по 2020 г. С целью изучения морфологических изменений сетчатки после остро возникшего субмакулярного кровоизлияния требуется соблюдение принципа мультимодальной визуализации, позволяющей установить прогностические критерии восстановления зрительных функций, а также способствующей выбору тактики хирургического лечения. Данная проблема мало изучена и требует проведения дополнительных клинических исследований.

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Субмакулярное кровоизлияние, геморрагическая отслойка сетчатки, возрастная макулярная дегенерация

Короткий адрес: https://sciup.org/149134977

IDR: 149134977

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