Статьи журнала - Re-health journal
Все статьи: 640
Technical capabilities of ultrasonic diagnostics
Статья научная
Instrumental diagnosis of diseases of the paranasal sinuses remains an urgent problem in practical otorhinolaryngology. The method used to identify sinusitis should be simple to perform, fast, safe and acceptable for screening diagnostics.
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Статья научная
This article presents the results of experiments with natural and artificial feeding, as well as the effect of artificial feeding on the development of offspring, the structural and functional functioning of its endocrine system, in particular, on the national adrenal glands. For the experiment, rat pups of white outbred rats of 1, 3, 7, 14, 21 and 30 days were used. Animals were divided into 2 groups of control and experimental. The control group were puppies rats born from intact females and fed a natural diet. The experimental group of animals up to 7 days was transferred to artificial feeding.These experiments were started at the Problem Biophysical Laboratory of the Tashkent Medical Academy under the guidance of Academician of the Academy of Sciences of the Republic of Uzbekistan K.A. Zufarova. Our data on the development of the offspring of rats in the period of early postnatal ontogenesis against the background of artificial feeding indicate a lag in growth and development, as well as a decrease in the mass of internal organs, including the adrenal glands. Thus, on the basis of our research, it was established that, against the background of artificial feeding, starting from 7 days after birth, the lag of the rat develops, resulting in a decrease in body weight, body length and mass of internal organs. organs for 14-21 days of development.
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The effectiveness of experimental herbal medicine for atherosclerosis with saponins
Статья научная
Статья посвящена вопросам фитотерапии атеросклероза тритерпеновыми сапонинами. Профилактика и лечение болезней растительными лекарствами известно с древних времен. Главным преимуществом является возможность их применения для профилактики и лечения атеросклероза и связанных с ним сердечно-сосудистых заболеваний. Общепринятым считается, что профилактика позволяет предотвратить и/или отсрочить сердечно-сосудистые заболевания. Но удается это не всегда, поэтому внимание исследователей привлекают препараты растительного происхождения. Общеизвестными считаются их преимущества, в сравнении с синтетическими препаратами. Экспериментальный атеросклероз был моделирован на кроликах. Фитотерапия представлена изучением растительных тритерпеновых сапонинов: леонтозид, дипсакозид и ладыгинозид. Выявлено, что наиболее высоким эффектом на атеросклероз кроликов показал ладыгинозид, который в сравнении с животными холестеринового контроля, приводит к снижению атерогенных поражений в 3,77 раз. Следующим идет дипсакозид, снизивший поражение атеросклерозом в 3,70 раза. Третье место занимает леонтозид, который уменьшил атерогенные поражения в 3,22 раза.
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Статья научная
Objective: Hyperprolactinemia is one of the most common endocrine disorders and can affect both genders at any age. The annual incidence of hyperprolactinemia in women is 8.7 per 100,000 individuals [5], and in the age group of 25-34 years, it increases to 29.3 cases per 100,000 population [3]. The most common causes of hyperprolactinemia include pituitary adenoma, intracranial tumors, medication use, primary hypothyroidism, and chronic kidney failure. Aim: To study the relationship of hyperprolactinemia with the immunohistochemical and morphological characteristics of breast cancer in women. Materials and methods: The study included 100 female patients with breast cancer associated with hyperprolactinemia. To achieve the set objective, all patients were divided into two groups: Group I - 70 women with hyperprolactinemia associated with breast cancer, and Group II - 30 patients with breast cancer and normal prolactin levels. Results: The study included 70 patients with hyperprolactinemia associated with breast cancer (Group I) and 30 women with breast cancer without hyperprolactinemia (Group II, the control group). The age of patients in the first group ranged from 29 to 65 years (mean age in the main group was 49 ± 11.7). In Group II, the age ranged from 19 to 65 years (mean age was 45.2 ± 13.2). Conclusion: Analysis of clinical and laboratory indicators in women with hyperprolactinemia (Group I) associated with breast cancer (BC) revealed a significant predominance of mastalgia (91.4%), nipple edema (53.3%), and breast edema (53.3%) accompanied by the lactoreia-dysmenorrhea syndrome. In contrast, Group II showed a significant prevalence of classical breast cancer symptoms, such as bloody nipple discharge (92%), orange-peel skin (60%), breast redness (40%), and axillary lymph node enlargement (40%). The study of the correlation between histological and molecular subtypes with prolactin levels revealed a predominance of invasive ductal carcinoma in 13 cases (19%), adenocarcinoma in 11 cases (16%), and medullary carcinoma in 10 cases (14.3%) in Group I.
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The relevance of the treatment of aplastic anemia
Статья научная
Aplastic anemia is a disease in which the bone marrow does not produce enough blood cells. Deficiency of all blood cell types - white blood cells (leukocytes), red blood cells (erythrocytes) and platelets - can lead to the formation of a disease called pancytopenia. For the treatment of aplastic anemia, medications, blood transfusions, or bone marrow transplants (stem cell transplants) are performed. Treatment of this disease is very topical. This will be discussed in this article.
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The role of endocrinological changes and obesity in the pathogenesis and origin of psoriasis
Статья научная
In spite of the fact that many developments are recorded in the treatment and pathogenesis of psoriasis, its etiology still remains obscure. Psoriasis is a chronic, common skin disease, which affects the patient’s quality of life to the highest degree. Several exogenous factors and endogenous hormonal changes may act as triggers for psoriasis. The skin possesses a true endocrine system, which is very important in multiple systemic diseases. A number of conditions are associated with psoriasis, and its severity can also be influenced by hormones and obesity. Hormones which can influence the psoriasis clinical manifestations: glucocorticoids, epinephrine, thyroid hormones, prolactin, sex hormones and insulin.
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The role of lipid metabolism in the development of biliary diseases
Статья научная
A diverse spectrum of diseases affects the biliary system, often presenting with similar clinical signs and symptoms. These conditions include gallstones, acute calculus cholecystitis, acute acalculus cholecystitis, Mirizzi syndrome, chronic cholecystitis, cholangitis (recurrent pyogenic, primary sclerosing, primary biliary, autoimmune), biliary tract malignancies, biliary tract cysts, and others. Metabolism also plays a role in the development of these diseases. This article discusses the role of lipid metabolism in the development of biliary diseases.
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The role of proinflammatory cytokines in metabolic syndrome
Статья научная
The article covers the literature data informing the relationship of proinflammatory cytokines and obesity. The study of the pathophysiological mechanisms underlying obesity is crucial for the development of effective therapeutic strategies to combat this disease, which causes many pathologies, including the development of a "pro-inflammatory condition". In this regard, the study of proinflammatory cytokines is of particular importance in the development of metabolic syndrome.
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The usage of passive voice in medical journal articles
Статья обзорная
Authors, editors, publishers as well as English teachers have a choice about the role of the passive voice in their publications, and there is considerable debate about what that role should be. On one side of the debate is the argument that medical writers should minimize use of the passive voice because it is less clear, less forceful, and more verbose than active voice alternatives. The opposing argument is that the passive voice should be the predominant style of most types of medical writing because the passive voice reflects the objectivity of the scientific method.
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Статья научная
The aim of the study was to study the state of changes in the mucous membrane of the edges of duodenal ulcers in conjunction with infection with Helicobacter pylori in patients with duodenal ulcer (DU) with colonic dysbiosis under the influence of transcranial electrical stimulation and CMV therapy. The studies were carried out in 57 patients with DU with intestinal dysbiosis (DK). There were 22 women, 27 men. At the age of 18-65 years. All patients were diagnosed with DU with DC. Patients were divided into 3 groups, except for the control group: patients who received CMW-therapy in the area of the duodenal triangle - 23 patients, patients who received transcranial electrical stimulation (TES) therapy - 19 patients, patients who received CMW-therapy in the area of the duodenal triangle and TES therapy - 15 patients. The control group consisted of patients (20 patients) receiving standard eradication therapy. Thus, the therapy regimens with the inclusion of physical factors, namely, CMW-therapy on the area of the duodenal triangle and TES therapy, in terms of their morphological effectiveness, significantly exceeded the similar direction of the effects of standard eradication therapy regimens. It is possible that the higher efficiency of schemes with the inclusion of physiotherapy is associated with a more positive dynamics of these schemes in relation to the elimination of Helicobacter pylori infection.
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The value of English in the professional development of medical staff
Статья научная
This article reveals the inherent role of the English language in the professional activities of a doctor, the opportunities provided to the specialist in medicine who speaks English. The article also discusses a number of problems associated with the study of English in medical schools, and therefore offers some possible solutions to these problems.
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Traumatic cataract among children
Статья научная
The analyzed results of complex examination and treatment of 126 juniors having different traumatic eye damage. The extraction of catarrhal masses was carried out in 46,2% cases with the implantation of back chamber lenses. Primary surgical therapy treatable of the wound with the extraction of cataract was performed on 24,6% of the patients. Timely initial surgical therapy treatable with the extraction of cataract masses and the implantation of back chamber IOL is considered to be the optimal way of surgical treatment of swelling traumatic cataract.
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Treatment of colorectal cancer and the role of vitamin D in this process
Статья научная
Colorectal cancer is a dangerous disease. Surgery, chemotherapy, radiation therapy and immunotherapy play a key role in its treatment. It is also now known to science that there is a link between vitamin D and this disease. Therefore, in this article, along with all the treatments, we will focus mainly on vitamin D.
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Treatment of hypertrophic cardiomyopathy: new methods
Статья научная
Hypertrophic cardiomyopathy (HCM) is a disease in which the heart muscle becomes abnormally thick (hypertrophied). The thickened heart muscle can make it harder for the heart to pump blood. Hypertrophic cardiomyopathy often goes undiagnosed because many people with the disease have few, if any, symptoms and can lead normal lives with no significant problems. However, in a small number of people with HCM, the thickened heart muscle can cause shortness of breath, chest pain or problems in the heart's electrical system, resulting in life-threatening abnormal heart rhythms (arrhythmias) or sudden death. Currently, a number of studies are being conducted by scientists and new methods of treating this disease are being developed. We will discuss this in this article.
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Uchinchi avlod tutqanoqqa qarshi vositalar: farmakodinamikasi, farmakokinetikasi va qo‘llanilishi
Статья научная
Tahliliy maqolada yangi avlod epilepsiyaga qarshi vositalar: eslikarbazepin, lakosamid, retigabin, perampanel, everolimus, brivarasetam va zonisamidning farmakologik xususiyatliri ko‘rib chiqiladi. Farmakokinetikasi, ta’sir mexanizmlari, dorilar bilan o‘zaro ta’sirlari, qo‘llashga ko‘rsatmalar va nojo‘ya ta’sirlari haqida ma’lumotlar keltiriladi. Ushbu preparatlar avvalgi qo‘llanilgan birinchi va ikkinchi avlod tutqanoqqa qarshi vositalaridan samaraliroq va xavfsiziroq deb tan olingan. Yangi ochilgan epilepsiyaga qarshi vositalarning ko‘pchiligi fokal hurujlarni, shuningdek spesifik epileptik sindromlar (Lennoks-Gasto sindromi, Dreve sindromi) hamda tuberoz sklerozlarni davolashda ishlatiladi. Preparatlarning ta’sir mexanizmi, farmakokinetik xususiyatlari, klinik samaradorligi va nojo‘ya ta’sirlari bemorlarni davolashda individual yondashuvni talab qiladi. To‘g‘ri tanlangan davo sxemasi epileptik hurujlarni nazoratga olish hamda asoratlar rivojlanishini oldini olishga imkon beradi. Epilepsiyaga qarshi vositalarni tayinlashda ularning farmakokinetikasi va farmakodinamikasini hisobga olish lozim.
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Umurtqa pog’onasi bo’yin qismi lateral stenozining zamonaviy nur diagnostikasining xususiyatlari
Статья научная
Bo’yin o'murtqa stenoz (tor o'murtqa kanal, tor orqa miya kanali, o'murtqa kanalning torayishi) patologiyaning alohida nozologik shakli sifatida XX asrning 50-yillarida H. Verbiest tomonidan batafsil tavsiflangan. Bel stenozning namoyon bo'lishini baholashda klassik neyrogen intervalgacha klaudikatsiya sindromi, bo’yin stenoz esa miyelopatik yoki miyeloradikulopatik sindrom deb tan olingan.
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Vascular tone and endothelial dysfunction genes polymorphism in preeclampsia
Статья научная
Five genes polymorphism of «endothelial dysfunction» and «vascular tone: endothelial nitric oxide synthase NOS3, aldosterone synthase, angiotensin II receptor and guaninebinding protein were studied in case-controlled sample of 78 patients diagnosed preeclampsia and 29 healthy controls. Results of this study demonstrate the presence in NOS3 gene risk and protective markers in the development of PE. Genetic associations performed in this study may be used as genetic markers of PE susceptibility, which will allow timely group risk patients, to work out correct treatment, and preventive measures.
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Статья научная
The features of the course of COPD in combination with diabetes mellitus were studied using X-ray and MSCT methods. The pulmonary component and systemic manifestations that aggravate the disease have been identified. The manifestations of diabetes mellitus are based on micro- and macroangiopathies that affect pulmonary microcirculation. Standard radiography did not reveal significant differences between the examined groups of patients with COPD. Diagnostically significant for COPD during MSCT is a symptom of an expiratory "air trap", in combination with expansion and deformation of the bronchi, up to bronchioectasis. Changes characterizing microangiopathy are pathognomic: dilated parenchymal vessels, focal-like shadows of vascular genesis, a distinct shape of vessels, which are considered as a consequence of specific microangiopathy and fibrotic changes in COPD.
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Статья научная
Dolzarbligi. Xoledoxolitiaz mexanik sariqlikning eng ko‘p uchraydigan sabablaridan biri bo‘lib, dekompressiya kechiktirilgan holatlarda xolangit va biliar sepsis rivojlanish xavfi yuqori ekanligi aniqlangan. Maqsad. Xoledoxolitiaz bilan bog‘liq mexanik sariqlikda tashxis qo‘yish va jarrohlik taktikasiga oid zamonaviy adabiyot ma’lumotlarini tahlil qilish. Materiallar va usullar. PubMed va Scopus ma’lumotlar bazalarida 2015–2025 yillar oralig‘ida chop etilgan ilmiy ishlar tahlil qilindi. Natijalar. MRXPG va endoskopik ultratovush tekshiruvining yuqori diagnostik aniqlikka ega ekanligi tasdiqlandi. Endoskopik papillosfinkterotomiya distal lokalizatsiyadagi toshlarda samarali hisoblanadi, laparoskopik xoledoxolitotomiya esa bir bosqichli davolash imkonini yaratadi.
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Статья научная
Bolalardagi qalqonsimon bez (QB) kasalliklari endokrinologiyaning eng muhim muammosi hisoblanadi. Oʻzbekistonda bolalardagi gipertireoz boʻyicha tadqiqotlar oʻtkazilmagan. Maqsad: tireotoksikoz boʻlgan bolalar va oʻsmirlarda QB xususiyatlari va morfologik tuzilishini aniqlash. Material va usullar: gipertireozi bor boʻlgan 213 ta bola va oʻsmirda umumiy klinik, biokimyoviy, immunologik, instrumental va statistik tadqiqot usullari bilan foydalangan. Natijalar: Greyvs kasalligi (GK) boʻlgan bolalar guruhida 95% hollarda 2 darajali buqoq tashxisi qoʻyilgan, oʻrtacha tireotoksikoz ustunlik qilgan (80%), 20,7% tugunli/koʻp tugunli buqoq, 3,3% ida qalqonsimon bezning differensial saratoni (QBS) aniqlangan. Xulosa: Yod tanqisligi sharoitida yuvenil gipertireoz hollarda 3,3% bolalar va oʻsmirlarda GK differensial QBS bilan birga keladi.
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