Relation of antistress and geroprotective effects of deuterium depleted water in aging female rats
Автор: Kit Oleg I., Shikhliarova Alla I., Zhukova Galina V., Dzhimak Stepan S., Barishev Mikhail G., Kurkina Tatiana A., Shirnina Elena A., Protasova Tatiana P.
Журнал: Cardiometry @cardiometry
Рубрика: Original research
Статья в выпуске: 10, 2017 года.
Бесплатный доступ
The use of deuterium depleted water (DDW) in a dosing regimen of 25-30 ml per day for five weeks in aging female rats (20-22 months) contributed to the overall correction of agerelated disorders of the adaptive status, estrous cycle regulation and nonspecific resistance, as well as the appearance of visually distinct signs of rejuvenation of the animals. The obtained results show the relation between the geroprotective effect of DDW and the development of the general nonspecific antistress adaptation reactions of calm and elevated activation that can serve as an experimental basis for the development of an effective method of geriatrics and prevention of cardiovascular diseases and degenerative processes in women in the peri and postmenopausal period.
Deuterium depleted water, aging female rats, estrous cycle, general nonspecific antistress adaptation reaction, neuroendocrine regulation
Короткий адрес: https://sciup.org/148308873
IDR: 148308873
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