Effects of cardiopulmonary bypass on liver function in patients undergoing cardiac surgery
Автор: Reddy A.P., Sunitha R., Thangavel P., Ramkumar J., Miller S.G.
Журнал: Cardiometry @cardiometry
Рубрика: Original research
Статья в выпуске: 27, 2023 года.
Бесплатный доступ
Cardiopulmonary bypass (CPB) might have several systemic impacts on organs such as the liver. This prospective research was designed to investigate the occurrence & significance of this shift in more depth.40 patients of cardiopulmonary bypass were chosen at random for the research. After coronary artery bypass grafting, total bilirubin, direct bilirubin, Alkaline Phosphatase (ALP), SGOT, & SGPT were determined preoperatively & post operation after 24, 48 hours. The liver function tests’ (LFT) post-operative value, in relation to above factors, was compared with preoperative value using t test. The results show a statistically significant increase (p ≤ 0.05) in total bilirubin, direct bilirubin, Alkaline Phosphatase, SGOT, & SGPT on post-operative days 1 & 2 in patients who had complex surgeries & valve replacement surgeries while on CPB. Low cardiac output may be related with a transient rise in hepatic enzyme levels following surgery. Throughout the post-operative period, hepatic enzyme levels were higher in patients with longer CPB durations.
Cardiopulmonary bypass, pre & post-operative results, liver dysfunction, hepatic failure
Короткий адрес: https://sciup.org/148326614
IDR: 148326614 | DOI: 10.18137/cardiometry.2023.27.194199
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