Pathogenetic substantiation for anti-tumor effectiveness of experimental electromagnetic therapy

Автор: Kit Oleg I., Komarova Ekaterina F., Shikhlyarova Alla I., Korobeinikova Elena P., Vanzha Ludmila V., Pozdnyakova Viktoria V., Dashkov Andrey V., Frantsiyants Elena M.

Журнал: Cardiometry @cardiometry

Рубрика: Original research

Статья в выпуске: 11, 2017 года.

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Aim The objectives to be pursued by our studies are to assess some effects made by experimental actions of ultra-low frequencies electromagnetic field (ULF EMF) in combination with the SCENAR therapy on morphological changes in lung tissues and the regulation structures considering tumor growth dynamics. Materials and methods We investigated sex hormone and prolactin concentrations in 156 male rates of outbred strains in the tumor growth dynamics in tissues of the lungs and the hypophysis, and we also studied morphological changes in the lung tissue. All animals were divided into two groups: the reference group, covering the rodents not affected by any exposures, and the experimental group of the rats, who were subjected to ULF EMF exposure in combination with the SCENAR therapy. Both therapeutic exposures were applied upon expiration of 1 week after tumor cell inoculation in a lung. Results The applied combination of the experimental therapy, involving the central and local electromagnetic actions, has resulted in the reliably established prolongation of life spans in tumor-bearing animals as well as in the negative dynamics in tumor growing; it has produced effects both on the hormonal homeostasis subsystems: the hypophisis and the lung tissue affected by the cancer tumor...

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Ulf emf, scenar, experimental tumor in lungs, antitumor effect, sex hormones, prolactin, hypophysis

Короткий адрес: https://sciup.org/148308833

IDR: 148308833   |   DOI: 10.12710/cardiometry.2017.11.5463

Список литературы Pathogenetic substantiation for anti-tumor effectiveness of experimental electromagnetic therapy

  • Kit OI. НЕЙРОЭНДОКРИННЫЕ, КЛИНИЧЕСКИЕ И МОРФОЛОГИЧЕСКИЕ АСПЕКТЫ РАКА ЖЕЛУДКА (Neuroendocrine, clinical and morphological aspects of stomach cancer). Novocherkassk, 2014.
  • Vodolazhskij DI, Kit OI, Maksimov AJu, et al. Communication of mutations of the EGFR gene with clinical and pathological features of lung adenocarcinoma in patients of the south of Russia. Klinicheskaja medicina. 2014;92-7:57-62.
  • Gudkov AB, Karpin VA, Kostrjukova NK, Lovkina ES. Biological effects of an ultraweak magnetic field. Moscow: Izd-vo «Jekologija cheloveka», 2004. 5 p.
  • Illarionov VE. Magnetotherapy. Moscow: Izd-vo LIBROKOM, 2009. 136 p.
  • Sidorenko JuS, Franciyanc EM, Komarova EF, et al. Induced malignant tumors in the lung of rats and anticarcinogenic effect of the ultra-low frequency magnetic field. Izvestija VUZov. Severo-Kavkazskij region. Estestvennye nauki. 2010;2(156): 89-91.
  • Shihljarova AI, Mar'janovskaja GJa, Barsukova LP, et al. Some Results and Prospects of Experimental and Clinical Investigation of the Antitumor Influence of Electromagnetic Nature Factors. Izvestija vysshih uchebnyh zavedenij. Severo-kavkazskij region. 2011;111-114.
  • Garkavi LKh, Zhukova GV, Shikhliarova AI, et al. Antitumor action and other regulatory effects of low intensity electromagnetic and chemical factors in an experiment. Biophysics. 2014;59(6):946-55.
  • Shevchenko AN, Shihljarova AI, Filatova EV, et al. Modified Intravesical chemotherapy of bladder cancer. Urologija. 2015;1:54-7.
  • Shihljarova AI, Protasova TP, Korobejnikova EP, et al. Optimization of brain processes and regulation of homeostasis in patients with lung cancer with central magnetic field influence. Mezhdunarodnyj zhurnal jeksperimental'nogo obrazovanija. 2013;8:114-9.
  • Anapaljan VH, Barsukova LP, Mar'janovskaja GJa, et al The use of polymodal factors in the practice of treatment of patients with colorectal cancer. Rossijskij zh-l gastrojenterologii, gepatologii, proktologii. 2008;19(5):186.
  • Atmachidi DP, Shikhlyarova AI, Rostorguev EE, et al. Effectiveness of transcranial magnetic stimulation in neurooncological patients. J Clin Oncol. 2015;33.
  • Shihljarova AI, Francijanc EM, Nepomnjashhaja EM, et al. Peculiarities of structural changes in lungs of rats of males and females with intravenous sarcoma inoculation 45. Voprosy onkologii. 2010;56(5):632-7
  • Komarova EF. Pathogenetic aspects of malignant neoplasms of the lung. Dissertation. Rostov-na-Donu, 2011
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