Ретрансплантация печени в современной концепции лечения её терминальных поражений (обзор литературы)

Автор: Ахмедов А.Р., Новрузбеков М.С., Гуляев В.А., Олисов О.Д., Луцык К.Н., Магомедов К.М., Казымов Б.И., Алекберов К.Ф., Аносова Е.Ю., Яремин Б.И.

Журнал: Вестник медицинского института "РЕАВИЗ": реабилитация, врач и здоровье @vestnik-reaviz

Рубрика: Донорство и трансплантация органов и тканей

Статья в выпуске: 5 т.13, 2023 года.

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Наиболее частыми причинами потери трансплантата печени являются первично нефункциопирующий трансплантат (ПНФТ), тромбоз печёночной артерии (ТПА), рецидивирующие исходные заболевания и хроническое отторжение. Ведущим показанием к ретрансплантации у детей является ТПА. Годичная выживаемость после ретрансплантации составляет примерно 75 %. Снижение затрат на ретрансплантацию органов и экономическая эффективность процедуры остаются спорными вопросами. Математическое моделирование выявило несколько значимых донорских и реципиентских факторов, влияющих на исходы повторной трансплантации. Несмотря на этические и экономические соображения, ретрансплантация является единственным вариантом для пациентов, перенёсших трансплантацию, у которых трансплантаты не прижились. Решение о ретрансплантации должно приниматься с некоторой осмотрительностью, с полным мультидисциплинарным подходом в больших многопрофильных центрах трансплантации.

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Трансплантация печени, первично нефункционирующий трансплантат, лист ожидания, ретрансплантация, релистинг

Короткий адрес: https://sciup.org/143181080

IDR: 143181080   |   DOI: 10.20340/vmi-rvz.2023.5.TX.1

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