Статьи журнала - Cardiometry
Все статьи: 527
Статья научная
The aim was to study changes in the functioning of the hypothalamic-pituitary-gonadal (HPG) axis in BALB/c Nude mice of both sexes with multiple primary malignant tumors (MPMTs). The BALB/c Nude mice (n=84) of both sexes were divided into groups as follows: intact males and females (n=14), a reference group of mice of both sexes with standard subcutaneous inoculation of B16/F10 melanoma (n=14); the main group of mice with the reproduction of the MPMT model (n=14); B16/ F10 melanoma and Lewis carcinoma were inoculated into mice sequentially subcutaneously on two sides: one on the left side and the other on the right side. After 15 days of the growth of the malignant tumors, GnRH, LH and FSH contents were determined by ELISA using standard kits in 1% of the homogenates of the hypothalamic and pituitary tissues, and estradiol content (E2) was determined in 10% homogenates of ovaries and testes, as well concentrations of testosterone (T) and progesterone (P4) were identified in blood serum with the standard RIA kits (Immunotech, Czech Republic). Results. In the hypothalamus in females of the reference and main groups, the level of GnRH increased by 2.5-4 times, and in males it decreased by an average of 3.1 times; in response to those changes in animals of both sexes in the reference group and in the main group only in females in the pituitary gland the level of LH increased by 1.3-1.6 times, however a decrease in FSH in all groups was more pronounced in females: by 7.8-13.7 times and less pronounced in males: by 1.4-1.7 times (р˂0, 05). In the gonads of females, the level of E2 increased, but the levels of T and P4 decreased, while P4 increased in males. Blood parameters did not reflect hormonal changes in the organs. Conclusion. Abnormalities in the HHG axis performance, along with primary immunodeficiency, play a decisive role in overcoming antitumor protection for uncharacteristic malignant tumors.
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Effect of COVID-19 pandemic: tourism and hospitality industry
Статья научная
The coronavirus, which causes COVID-19 disease, has unimaginably affected every industry. Among all industries, the tourism and hospitality industry is considered the worst-hit industry, contributing 9% of India’s total GDP; this paper presents an overview of the Indian tourism and hospitality industry before COVID-19. While sending out survey forms, we included general questions like gender, occupation, age, level of education, yearly income, what used to be their choice of location for a holiday before COVID-19, how much they yearly spent on holiday, how they plan their holiday trip, to understand the basic details and reliability of participants, also we did not ask the name of a participant to maintain the anonymity and privacy of a participant, which helped us to get an accurate data. How customers’ changed mindsets different priorities forced the tourism and hospitality industry to change the way of providing service also how the changed time has forced businesses to look for other opportunities to survive in the industry, Moreover here we have test different Sanitization and safety measurements using Friedman test to understand what are the factors that can affect the business of tourism and hospitality industry after the COVID-19 pandemic, as observed by Assaf & Scuderi.
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Effect of diabetes type-II on eye disease and its risk factors; a logit model analysis
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To know the effect of Diabetes type-II on Eye disease and its risk factors in a tertiary eye care hospital in Karachi. This was a cross-sectional study with retrospective data collection. The data was retrieved from January to June 2019 from the Hospital Information Management System (HIMS) software of the Institute. Non-probability purposive sampling method was used to collect data. Inclusion criteria were all the diabetics type-II patients came for routine check-ups at Diabetes Eye Department irrespective of age, gender and duration of diabetes. Statistical analysis was done using STATA version 13.0 software for windows. A total of 6090 cases were analyzed. Mean age of the participants was 51.01±10.8 years. There were 2954 (48.5%) male and 3136 (51.5%) female observed in this study. Table 1 shows the results of the binary logistic regression analysis with coefficients and their standard errors (S.E.), Wald test values, p values, odd ratios, and 95% confidence intervals for odds ratios. When all explanatory variables treat as continuous variables, we found that all variables which include age, height, random blood sugar (RBS) and duration of diabetes was statistically significant at the significance level 0.05 except weight and fasting blood sugar (FBS) for individual regression slope coefficients. This study reveals findings through binary logistics regression analysis. It indicates that there is an association found in the patients of eye disease with age, height, weight, RBS, FBS. This stated that there were some risk factors observed in these variables related to eye disease. Those who have the disease have risk factor to developed the others associated disease
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Effect of slow coronary flow on signal-averaged electrocardiogram
Статья научная
The slow flow coronary or decreased coronary TIMI flow rate is characterized by delayed pacification of coronary vessels in the absence of any evidence of obstruction coronary artery disease and is detected by coronary angiography. In the present study, we aimed to evaluate the effects of slow coronary artery flow on signal-averaged electrocardiogram (SAECG) as a possible indicator of increased risk for ventricular arrhythmias and sudden cardiac death.
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Effect of smoking on the cardiovascular system of man
Статья научная
The article presents the state of the cardiovascular system of smokers with different periods of tobacco smoking. From the results of our studies, we can conclude that smoking tobacco in men results in a significant increase in heart rate, systolic blood pressure, a significant reduction in P, PQ and QT times, an insignificant increase in diastolic blood pressure and a decrease in QRS duration.
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Статья научная
The triage system is meant to be implemented in all (Accidental & Emergency Departments) so as to help and determine the relative priority of individual patient needs. Emergency patients are to be given immediate treatment, while those with non-acute symptoms may have to wait longer (Lucke et al., 2021). Assessment process during the triage need to be balanced with the extent of patient flow, as expanding the assessment process during triage may slow down the patient flow and may lead to delay in emergency service provision (Lucke et al., 2021).Through the use of computer-generated reports, archival data records for two months from the ED of the Bahria International Hospital in Lahore, Pakistan to assess the effectiveness of patients triage flow model. The results of this quantitative study showed that the patient flow model had a considerable temporal effect. Including 16 females, 25 were male and 25% average waiting was more than 240 mints. The ability to decrease patient wait times while enhancing patients quality of care and health outcomes is one of the social change implications. A quantitative study would produce data that would assist medical staff by shortening the wait times for patients.
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Effectiveness of blockchain to solve the interoperability challenges in healthcare
Статья научная
This study aims to explore the potential of Blockchain to transform healthcare, build the patient-driven healthcare ecosystem rather than the current institutional driven and enhance the privacy, security, and interoperability of healthcare data and check the counterfeit drugs. Interview excerpts from Industry experts/developers in the field of IT and experience from the implementation of the technology in the financial world will help understand its viability in healthcare. Consulting with domain experts is a qualitative process that involves comprehending the perception of the experts. The research paper will help the healthcare sector lay down future business strategies to redefine its businesses by overcoming the increasing threat on patients’ private data and resolving complex supply chain issues. A decentralized ledger can prevent massive revenue loss due to counterfeit drugs to track and verify each drug’s movement on the unchangeable record. The primary and secondary research is original, adding its authenticity with interview excerpts of domain experts. The results of this research paper will help identify the transparency, immutability, cost-saving, and streamlining of business to be brought by Blockchain in health care. It would be the transformational journey from innovation to market the quality products to the end consumer.
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Статья научная
Pregnancy is the period of gestation from the fertilization of an egg, through development of a fetus, and ending at birth of the baby. A woman’s desire for, and cold pack of, pain relief during labour are influenced by many factors, including her expectations, the complexity of her labour and the severity of her pain. Objectives: To assess the pre-test and post-test level of pain perception during active phase of labour among parturient mothers both in experimental and control group, effectiveness of cold pack on reduction of pain perception during active phase of labour among parturient mothers in the experimental group, association between the level of pain perception during active phase of labour among parturient mothers with their selected demographic variables. Methods: An experimental research design was adopted for the study with 60 samples who met the inclusion criteria were selected by purposive sampling technique. Semi structured interview method was used to collect the demographical and obstetrical data, Wong Baker Scale tool was used to measure the level of pain. Result: The study shows that there is a significant difference between the posttest levels of pain perception during active phase of labour among parturient mothers in the experimental group than in the control group. Conclusion: There was a significant association in the post test level of pain perception among parturient mother in the experimental group than in the control group at p function show_abstract() { $('#abstract1').hide(); $('#abstract2').show(); $('#abstract_expand').hide(); }
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Статья научная
Hyper tension is often known as high blood pressure. It is a serious medical condition that raises the risk of heart attack, stroke, renal failure, and blindness. When the systolic blood pressure readings are greater than or equal to 140 millimeters of mercury and the diastolic blood pressure readings are greater than or equal to 90 millimeters of mercury on two different days, hypertension is diagnosed. It is one of the leading causes of death in the world. Of the assessed 1130000000 people who have hypertension, fewer than 1 in 5 have it under control. The main contributors to the increase in hypertension are unhealthy diets, physical inactivity.In 2025; anpredictable 1.56 billion adults will be living with hypertension.).The aim of the study is to assess the Awareness regarding Hypertension among hypertensive patient.In this study, the pre-experimental research design was accepted. The samples of the present study were patients with pre hypertension and stage -I hypertension. Conclusion: This pilot study concludes by proving the efficiency of health education on Knowledge of hypertension among rural adult hypertensive patient.
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Статья научная
Diabetic populations are anticipated to increase from 171 million to 366 million in 2030, with the greatest rates in India, China, and the United States. Diabetes is a metabolic disorder that generates high glucose levels in the blood. The World Health Organization (WHO) estimates that India has over 70 million diabetics and is on its way to become the world’s diabetes capital. Patients had a 7.20 knowledge score on the pretest and an 11.78 knowledge score on the posttest, resulting in a mean difference of 4.58 knowledge score, this is a considerable and statistically significant increase in knowledge. The relationship between the patient’s demographic characteristics and their post-test knowledge score..Patients with a high education level and longer disease duration got a higher knowledge score than those with a lower level of education and a shorter duration of illness. The chi square test and Yates corrected chi square test were used to corroborate it.
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Статья научная
Background: Kidney is a vital organ and the main function is to remove waste products and excess water from the blood. Different kidney pathogenesis challenges the function of human body and puts human life danger. Two such important pathogenesis is acute and chronic renal failure. The incidence of acute renal failure has been estimated to be 209 patients per million populations per year and 37% of patients treated in intensive care units. Muscle cramps also can occur when patients are below dry weight. The severe muscle cramping experienced near the end of the hemodialysis treatment and persisting for a time after hemodialysis often is due to dehydration. Treatment for cramping varies from unit to unit. When patients are having cramping and have low blood pressure, the staff may give normal saline. Aim of the study: The main aim of the study to assess effectiveness of isotonic exercise on muscle cramps among hemodialysis patients. Methods: Quantitative research design was adopted for the study with 60 samples which met the inclusion criteria were selected by convenience sampling technique. Demographic variables data were collected by using a multiple-choice questionnaire followed by Pretest was conducted by using muscle cramp assessment tool for both experimental group and control group. Isotonic exercise was given 10 to 15 minutes at one session for experimental group Post test was conducted by using muscle cramps assessment tool and for both experimental group and control group. Result: Out of 60 samples, The calculated student Independent ‘t’ test value of t = 2.500 was found to be statistically highly significant at p function show_abstract() { $('#abstract1').hide(); $('#abstract2').show(); $('#abstract_expand').hide(); }
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Effectiveness of modified Manchester triage flow model regarding patients’ waiting time
Статья научная
Triage is a French word meaning to sort or to choose. Triage is therefore a process whereby each patient is prioritized amongst the randomly approaching patients in the Accident & Emergency Department/rescue area for emergency care ( Zachariasse et al., 2021). Sorting of patients into priority categories is often performed by an experienced doctor/surgeon or a senior health professional/nurse. The triage nurse/health professional shall quickly assess the patient’s condition, interpret the clinical features and then exercise interventions in the early phase to prevent deterioration and death (Soler-Sanchis, Martínez-Arnau, Sánchez-Frutos, & Pérez-Ros, 2022). The objective of the triage is to defer a patient who can wait, while give priority to those who are in imminent danger, and whose life can be saved by a timely intervention (Costa, Nicolaidis, Gonçalves, Souza, & Blatt, 2020). The Manchester Triage System is used to maintain a consistent method of prioritising and assessing patients, allowing for thorough audits and improved patient safety. Emergency departments (EDs) are seeing more difficulties globally as a result of an increase in patients and an inability to adjust capacity to meet demand. This is against a background of decreasing hospital resources. Consequently, ED crowding has become a great, international phenomenon (Zachariasse et al., 2021). The Manchester Triage System is one of Europe’s most widely used triage systems, considering five levels to prioritise patients in the ED: level 1 (red), immediate; level 2 (orange), very urgent; level 3 (yellow), urgent; level 4 (green), standard; and level 5 (blue), non-urgent (Brutschin, Kogej, Schacher, Berger, & Gräff, 2021) Patient flow model refers to the movement of patients through health care settings involves the medical care, physical resources, and internal systems needed to get patients from the point of admission to the point of discharge while maintainingand patient/provider satisfaction (Tlapa et al., 2020). The major facility for urgent medical difficulties is a hospital emergency department (ED), which is a complex system with erratic demands.
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Статья научная
Non-Stress test is a non-invasive test performed over 28 week of gestation for detection of ante partum fetal surveillance. Maternal positioning can have an impact on both the mother’s and fetal physiological well-being. Objective: Assess and compare the effectiveness of maternal positions on bio physiological parameters of the fetus during NST. Methods: Quantitative quasi-experimental pretest, posttest only research design, 60 mothers were selected by random sampling technique. Maternal, fetal bio physiological parameters tool was used. The mothers were placed in left lateral, supine position while performing NST and fetal parameters were monitored and interpreted. Mother vitals also monitored. Results: The post test score of fetal reaction in supine was 4.20±1.16 and in lateral 4.90±0.31. The calculated independents’ test value of t = 3.205 was found to be statistically significant at p
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Статья научная
Obsessive-compulsive disorder frequently have insomnia, and those with acute insomnia who also have mental comorbidities without therapy, they are more likely to develop persistent insomnia. We present a case of OCD with acute insomnia that was successfully treated with early non-pharmacological sleep psychiatry intervention. Sleep is necessary for brain function and the maintenance of cognitive and emotional processes. Insomnia and anxiety problems are common, and they’re linked to a lot of damage and disability. In addition to being strongly comorbid with major depressive illness, there is evidence that sleeplessness and anxiety disorders frequently co-occur. The majority of insomnia psychological therapies include sleep hygiene. In terms of clinical practice, these instructions are a solid place to start. Obsessive-compulsive disorder is associated with sleep difficulties. Sleep difficulties are also common in people with obsessive-compulsive disorder, with up to 48% reporting them. Obsessive compulsive disorder research reveals a link between specific sleep habits and clinical factors such the severity of obsessive-compulsive symptoms, treatment resistance, and the age at which the disorder.
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Статья научная
Obsessive-compulsive disorder frequently have insomnia, and those with acute insomnia who also have mental comorbidities without therapy, they are more likely to develop persistent insomnia. We present a case of OCD with acute insomnia that was successfully treated with early non-pharmacological sleep psychiatry intervention. Sleep is necessary for brain function and the maintenance of cognitive and emotional processes. Insomnia and anxiety problems are common, and they’re linked to a lot of damage and disability. In addition to being strongly comorbid with major depressive illness, there is evidence that sleeplessness and anxiety disorders frequently co-occur. The majority of insomnia psychological therapies include sleep hygiene. In terms of clinical practice, these instructions are a solid place to start. Obsessive-compulsive disorder is associated with sleep difficulties. Sleep difficulties are also common in people with obsessive-compulsive disorder, with up to 48% reporting them. Obsessive compulsive disorder research reveals a link between specific sleep habits and clinical factors such the severity of obsessive-compulsive symptoms, treatment resistance, and the age at which the disorder.
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Effectiveness of swallow therapy on swallowing ability among patients with cerebrovascular accident
Статья научная
Cerebrovascular accident occurs when the blood supply to the brain is disturbed in some way. As a result the brain cells are deprived of oxygen. It is also known as stroke. It is being observed as a rapidly growing problem and an important cause of illness and death in Saudi arabia. The major problem of cerebrovascular accident is paralysis of swallowing muscles leading to swallowing difficulty which is known as dysphagia. It involves the mouth, throat and esophagus. The goal of this study was to see how swallow treatment affected patients with cerebrovascular accidents at Saveetha Medical College and Hospital in Chennai. The study used a quasi-experimental one-group pre- and post-test design. A total of 30 samples were chosen with care. The Mann Assessment of Swallowing Skills (MASA) was used to examine swallowing ability on regular basis. The results reveal that there is a significant difference in swallowing capacity before and after therapy when using descriptive and interferential statistical approaches. The average score of swallowing ability before swallow therapy was 155.0±16.34, while the average score after swallow therapy was 170.87±11.12. At p function show_abstract() { $('#abstract1').hide(); $('#abstract2').show(); $('#abstract_expand').hide(); }
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Effects of cardiopulmonary bypass on liver function in patients undergoing cardiac surgery
Статья научная
Cardiopulmonary bypass (CPB) might have several systemic impacts on organs such as the liver. This prospective research was designed to investigate the occurrence & significance of this shift in more depth.40 patients of cardiopulmonary bypass were chosen at random for the research. After coronary artery bypass grafting, total bilirubin, direct bilirubin, Alkaline Phosphatase (ALP), SGOT, & SGPT were determined preoperatively & post operation after 24, 48 hours. The liver function tests’ (LFT) post-operative value, in relation to above factors, was compared with preoperative value using t test. The results show a statistically significant increase (p ≤ 0.05) in total bilirubin, direct bilirubin, Alkaline Phosphatase, SGOT, & SGPT on post-operative days 1 & 2 in patients who had complex surgeries & valve replacement surgeries while on CPB. Low cardiac output may be related with a transient rise in hepatic enzyme levels following surgery. Throughout the post-operative period, hepatic enzyme levels were higher in patients with longer CPB durations.
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Effects of total table salt restriction on blood pressure
Статья научная
Aims. The aim of the study was to evaluate the effect of total omission of dietary salt intake on BP. Material and methods. The effects of total omission on the consumption of dietary salt over the BP, were evaluated for this study in a group of 30 hypertensive patients between 40-60 years old, uncontrolled, with monotherapy with angiotensin converting enzyme inhibitors or angiotensin II receptor antagonists. BP was recorded over three days at the same time, according to the guidelines of the American Heart Association for correct BP measurement in humans. The average of the three registers measurement was taken as baseline for comparison of the data. The only intervention was the total restriction of table salt and sauces with salt. The patients were followed monthly during the first five months recording BP under the same conditions that basal measurement, after this, were indicated to all the patients the consumption of salt 5g/day (provided by the researchers) and were followed for another five months in the same measurement conditions above...
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Статья научная
We have performed the study of the effects made by the automated plasmapheresis application on ischemic heart disease clinical manifestations, echocardiographic indices and heart rate variability in patients with exertional angina III-IV functional class. It has been found that the applied plasmapheresis method is capable to reduce the severity of the disease clinical manifestations and improve the echocardiographic characteristics of the heart, in particular, reduce the level of end-diastolic volume, and increase ejection fraction. The clinical effect is already apparent at the early stages of the treatment and remains unchanged even after 6 months thereof. Also revealed has been the normalization of heart rate variability, indicating a decreased activity of the sympathetic nervous system. It is concluded that the plasmapheresis method can be successfully used in practice by a wide range of hospitals, where patients with ischemic heart disease are monitored, including the ambulatory conditions.
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Отчет
Our results of analyzing effects made by electrode characteristics on the accuracy of the ECG signal parameters formation are presented herein. Analyzed is a correlation between the measured characteristics of the electrodes and a probability value that determines accuracy of the ECG signal parameters formation. With the help of scatter plots demonstrated is the strength of the correlation between the assessed variables. Our analysis of the obtained results shows that the harder is the contact agent in an electrode, the more accurate are the formed ECG signal parameters.
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