Статьи журнала - Cardiometry
Все статьи: 543
Статья научная
Aims Up to the present, ECGs have been classified on the basis of the analysis of the ECG curve shape. But this made impossible to classify many ECG shapes. The most promising methods for the classification must evaluate each of the 10 cardiac cycle phases both by their functions and hemodynamic parameters. The aim hereof is to develop the new classification principles for all possible ECG shape variations. Materials and methods The heart cycle phase analysis method is used to calculate the hemodynamic parameters in each of 10 phases, like the phase-related blood volumes and the level of contraction of the corresponding cardiovascular musculature determining its function dynamics in the cardiac cycle phase structure related to the compensation mechanism for maintaining normal hemodynamics. Results An ECG phase changes periodic table consisting of 10 groups of the actual ECG curves typical for the corresponding pathologies is proposed. Each group contains 4 levels of characteristic phase changes. Conclusion The ECG phase changes periodic table is the first attempt to classify the great variety of the ECG shapes. In this case the proposed system requires further investigations. It has been demonstrated that the theoretical concept of the table is in compliance with practice. Further it is planned to improve characteristics of every group and every level.
Бесплатно
Heart rate variability analysis: physiological foundations and main methods
Статья обзорная
The article presents the main provisions of the methodology for the analysis of heart rate variability (HRV), which is now actively and widely implemented in many fields of medicine and applied physiology. This methodology was first developed in space medicine, where, already during the first manned spaceflights, there was a need in operative assessment of the person's reactions and abilities to maintain high performance and good level of health under different stress conditions. The HRV analysis methodology is based on the measurement of a consecutive series of cardiac cycle durations, for which electrocardiography, rheocardiography, ballistic cardiography, etc., can be used. The resulting numerical series are subjected to mathematical analysis using statistical, spectral and other methods. The results are interpreted as medical and physiological criteria of the functional state of the organism. Based on the mathematical model, a probabilistic approach to the prediction of pathological conditions was proposed...
Бесплатно
Hedonic hunger: eating for desire and not calories
Статья научная
Hedonic hunger can be described as a state where an individual experiences recurrent feelings, thoughts, and desires about food in the absence of energy deprivation. Living in an obesogenic environment where cheap, tasty foods are available in plentiful amounts is one of the major causes of hedonic hunger development. Hedonic hunger can be analyzed using a power of food scale (PFS) which estimates appetite and not palatable food consumption. The current epidemic of obesity globally (termed as “globesity” by WHO) is seen to be majorly driven by the hedonic eating system and an imbalance in the energy homeostasis system. Previous studies indicate that hedonic hunger and obesity are associated, and a weak but no significant correlation exists between BMI and PFS score. It can lead to the development of various lifestyle disorders in the longer run. High levels of pleasure- driven hunger can even lead to detrimental health outcomes like poor glycaemic control, unhealthy dietary behavior, and increased lipid profile levels which are aggravated explicitly in cardiovascular diseases. With the adaptation to western dietary lifestyle, people are keener to opt for food options that can be damaging and harmful when low levels of self-control, dietary motivation, and healthy dietary habits are absent. Apart from the reward regulation system, which has a direct effect on hedonic hunger, certain external factors like emotional eating, meals and meal preparation, food cravings, sleep, physical activity, stress, social media, portion size, peer influence, an atmosphere of a restaurant can also promote more than required intake of food. This review article summarizes the above findings taking into account the plethora of research studies conducted so far.
Бесплатно
Статья научная
The results of this study have demonstrated the possibility of improving the efficiency of restoring hemodynamics and an adaptive status in patients with high-grade brain tumors by using transcranial magnetic therapy (TMT). The convenience and expediency of using the diagnostic criteria of the cardiac analyzer software CARDIOCODE consisted in obtaining complex digital data sets related to the main phase changes in the cardiac performance, energy supply and metabolism, associated with the corrective effect produced by TMT in the early postsurgery period. At the same time, it is noted that acting in concert by the cardiac performance can be provided against the background of the formation of a stable type of an integral reaction of calm activation
Бесплатно
Hierarchy of biological rhythms, chronodiagnostics and bio-feedback
Статья обзорная
An overview of the author’s original works dedicated to the hierarchy of biological rhythms, chronodiagnostics and bio-controlled chronophysiotherapy is presented herein. Stability of biosystems is based on harmony of discrete spectra of their biological rhythms with a spectrum of normal cosmoheliogeophysical rhythms. According to the extent, the nature and the sort of the phase-related, systematic and hierarchical desynchronoses it is possible to diagnose and forecast the condition and the resistance of biosystems at their respective level. An efficient management of life is possible by bio-synchronization of an external physical action with the phases of increasing of energy supply for the respective responses of a biosystem. A prerequisite for bio-resonance is a multi-frequency parallel resonant capture. An invariant ratio of biological rhythms periods in their hierarchy explains an exclusive sensitivity of the biosystems to biologically significant information influences under their high noise immunity to influences having a single constant frequency or showing an abnormal range of frequencies. Chronodiagnostics identifies disorders (desynchronoses) at the early preclinical stage of a disease. Bio-controlled chronophysiotherapy allows eliminating not only the symptoms, but also the causes of diseases (desynchronoses) in an organism.
Бесплатно
Histopathological analyses of breast cancer using deep learning
Статья научная
Deep Learning hosts a plethora of variants and models in Convolution Neural Networks (CNN), where the prudence of these methods is algorithmically proven when implemented with sturdy datasets. Much number of haphazard structures and textures are found in the histopathological images of breast cancer, where dealing with such multicolor and multi-structure components in the images is a challenging task. Working with such data in wet labs proves clinically consistent results, but added with the computational models will improvise them empirically. In this paper, we proposed a model to diagnose breast cancer using raw images of breast cancer with different resolutions, irrespective of the structures and textures. The floating image is mapped with the healthy reference image and examined using different statistics such as cross correlations and phase correlations. Experiments are carried out with the aim of establishing the optimal performance on histopathological images. The model attained satisfactory results and are proved good for decision making in cancer diagnosis.
Бесплатно
Статья
The 20th century was skeptical about magnetobiology. But the early experiments conducted by the American couple Barnothy, M. F., & Barnothy, J. M, who presented their data on the possibility of inhibiting the growth of tumors using strong magnetic fields, excited the world, and in the 60s last century, 3 international symposiums were held in Chicago, Rome, and Moscow to discuss that topical issue. By that time, a great progress in that scientific area was made by researchers from the Rostov Scientific School of Experimental Oncology
Бесплатно
History of space medicine: academician Vasily V. Parin, founder of space cardiology
Статья обзорная
Russian Academician Vasily V. Parin was one of the leading world scientists in the field of physiology of blood circulation. In this article his role in the development of the space cardiology, an important area of space medicine, is considered. The development and use in space flights of such methods as the analysis of heart rate variability and seismocardiography, creation of the onboard medical equipment is connected with the name of Vasily V. Parin. The monography “Space cardiology” issued in 1967 by Vasily V. Parin with co-authors has dictated and governed the development of this key area in science for many years ahead. The article presents the basic results of cardiological researches in space in the 70-90-s and in the beginning of the 2000s when the space cardiology made its progress keeping the tendencies and traditions created by Vasily V. Parin in the 60s.
Бесплатно
History of the arterial tonometer and the “Pranayama” gadget
Статья научная
An arterial tonometer that allows you to determine the pressure in the shoulder from the pulse wave of the radial artery without squeezing the vessels with a cuff, today remains an unattainable goal of many researchers due to the lack of suitable pulse wave sensors (PV). The article describes a mobile medicine device, which is a kind of “smart watch” with its original function of a human pulse wave analyzer. This function has become possible due to an introduction of a matrix fiber-optic sensor (MFOS) developed by a team of Russian scientists at the A. A. Blagonravov IMASH at the Russian Academy of Sciences. Features of the device that distinguish it from existing analogues are given below: 1) Capability to determine blood pressure with medical accuracy without squeezing blood vessels with a cuff, 2) Capability to diagnose the cardiovascular system and assess its condition taking into account the age of a person, 3) Capability to diagnose all human organ systems using spectral analysis of heart rate variability, 4) Capability to determine the code (modulation frequency) corresponding to the established disease after the diagnosis is established using this gadget, and to carry out targeted delivery of an increased amount of blood to the affected organ, 5) Capability to perform high-quality monitoring of blood pressure (over time). After diagnosis, the gadget determines the code (modulation frequency) corresponding to the established disease and promotes targeted delivery of an increased amount of blood to the affected organ. Treatment is carried out by organizing a certain respiratory rate, which, in turn, generates certain modulations of the heart rate. As a result, the affected organ receives an additional amount of blood and recovers.
Бесплатно
Отчет
Leonardo da Vinci perhaps was the first who paid attention to the energetic efficiency of existence of vortices emerging near sines of Valsalva and defining normal functioning (opening) of aortal valve. However up to now a fundamental problem of defining of mechanisms of mysterious energetic efficiency of functioning of cardio-vascular system (CVS) of blood feeding of the organism is still remaining significantly not solved and this is, for example, one of the main restriction for the creation of artificial heart and corresponding valve systems. In the present paper, results witnessing possible important role of the very hydro-mechanical mechanism in the realization of the noted energetic efficiency of CVS due to formation in the CVS of spiral structural organization of the arterial blood flow observed by methods of MRT and color Doppler-measuring in the left ventricular of the heart and in aorta (A.Yu.Gorodkov,et.al.).
Бесплатно
Identification of non-HLA antibodies in ventricular assist device recipients
Статья научная
Aims Recipients of ventricular assist devices (VADR) have a higher incidence to develop antibodies (Abs) against human leukocyte antigens (HLA). Non-HLA antibodies like major histocompatibility complex class I-related chain A (MICA) and autoantibodies against angiotensin type 1 receptor (AT1R) and endothelin receptor A (ETAR) are also implicated in the pathogenesis of acute rejection and allograft vasculopathy. We monitored non-HLA- and HLA-Abs in VADR up to one year after implantation. Materials and methods Sera of 56 VADR (54.1±12.8 years old, 50 men) were analyzed for Abs against HLA-, MICA-, AT1R- and ETAR several times over one year after implantation using ELISA and Luminex xMAP technology. Blood transfusions, gender and age were reviewed. Results Sera of 56 VADR (54.1±12.8 years old, 50 men) were analyzed for Abs against HLA-, MICA-, AT1R- and ETAR several times over one year after implantation using ELISA and Luminex xMAP technology. Blood transfusions, gender and age were reviewed. Conclusion Beside HLA- and MICA-Abs, VADR showed high titres of Abs against AT1R or ETAR, which underlines the necessity for monitoring non-HLA antibodies in VADR prior heart transplantation.
Бесплатно
Статья научная
The goals of this prospective observational study were to identify quantitative morphological factors that might aid in the prediction of PBMV outcome, as well as to define the function of 3D TEE in mitral valve evaluation. Material and Methods: The trial comprised seventy individuals who had isolated severe rheumatic Mitral Stenosis (MS) who were scheduled for PBMV between October 2017 and March 2021. Trans-thoracic echocardiography (TTE) was used for pre-procedural evaluation. Posterior to Anterior Leaflet Length Ratio (P/ALLR), Commissural Area Ratio (CAR), Doming Height (DH), and Calcification Score (Ca score) were also assessed using 2D and 3D-Trans-esophageal Echocardiography (TEE). Following that, all patients were monitored for three months. Results: We have had 50(71.5%) successful procedures and 20(28.5%) unsuccessful procedures. The additional parameters showed highly significant difference between successful and un-successful groups (P-value 0.6 and >0.55 by 2-D and 3-D TEE respectively, CAR ≤ 1.28 and ≤ 1.25 by 2-D and 3-D TEE respectively, DH > 1.2 cm by 2-D TEE, and Ca Score ≤ 2. Conclusion: In our research, we discovered that these characteristics may predict the result of PBMV and contribute value to the semi-quantitative methodologies we adopted to use.
Бесплатно
Статья научная
COVID-19, which also induced an economic downturn globally, has forced the organizations to suddenly implement remote working, creating many challenges for the employees. The fast spread of the virus may also create fear among the employees. It can have a detrimental impact on the mental well-being of employees. There exists inadequate research on this subject, which is not only new but also very important. The study aims to assess the impact of a sudden transition to remote working, economic downturn, and the fear of virus transmission on the mental well-being of employees in India, focusing on the triggers of anxiety & mental illness. The impact of anxiety-causing independent factors, including organizational support, worklife balance, isolation, fear of the virus, and recession, on mental well-being, was determined through a survey. The dependent factor, i.e., the severity of anxiety, was measured using GAD-7 questions. The independent factors were measured through structured questions. Statistical analysis of the data was carried out on SPSS. There were no significant differences in gender between severities of anxiety. Logistic regression revealed that Organizational Support significantly influenced the anxiety of employees. It was found that there exists a significant association between the severity of anxiety in Employee Assistance Program, Job Insecurity, Financial Impact, and Fear of getting the virus, Concern over Safety at Workplace, Home Environment and Deterioration in team collaboration
Бесплатно
Статья научная
Considering the diversity of proposed programs, various studies yielded different findings in this regard. The aim of the present study was to evaluate different types of exercise as a method of rehabilitation after acute myocardial infarction on the activity of the autonomic nervous system.
Бесплатно
Impact of inclusiveness on organizational commitment among employees of IT industry
Статья научная
Organizations continue to be challenged by diversity in their workforce. Hence it becomes imperative to nurture an inclusive workplace where all employees can co-exist and thrive. The primary objective of the current study is to examine the relationship between different constructs of inclusiveness and the organizational commitment of employees. Their search for the study is based on the data collected from multiple IT organizations across major cities (Delhi, Mumbai, Bangalore, and Pune) of India. A structured questionnaire was distributed. Multiple regression analysis was applied on the primary data obtained from 160 respondents to interpret the impact on the organizational commitment by different constructs of inclusiveness. The results from the study reveal that different constructs of inclusiveness (supervisor role, relationship with co-workers, and organizational practices) have a significant effect on the organizational commitment of an employee. The study highlights the importance of creating a sense of acceptance among employees of an organization through inclusive work culture, which ultimately enhances the commitment level of employees towards their organization.
Бесплатно
Impact of the academic performance grades on the blood picture in female students
Статья научная
The paper presents the blood picture patterns in female students with different average academic performance grades in their record book. An improvement in the academic performance of female students is accompanied by a significant decrease in the concentration of neutrophils, a significant increase in the level of lymphocytes and minor changes in other blood parameters. Thus, the level of neutrophils experiences a gradual decrease, reaching its minimum of 57.7% (P
Бесплатно
Impact on student behavior due to COVID-19 lockdown in India
Статья научная
This paper aims to comprehend the change & impact on students’ behavior during the COVID-19 Lockdown in India. The research is conducted by surveying to assess the different behavioral changes due to the COVID-19 spread. Novel coronavirus pandemic started from Wuhan, China, on 31/12/19. It spread across the globe affecting 1,00 000 people within the span of two to three months. People across the globe were affected not just in terms of physical health but also mental & psychological health, resulting in major changes in their behavior. The digital questionnaire assessed the status of pupils’ mental and psychical nature while the COVID-19 lockdown was on. The questions were framed to answer how students felt about the pandemic and how it has affected their day-today life. The results of the survey revealed the measure of the anxiety level of the students. The survey results are analyzed on SPSS, and Pearson Coefficient is the method used for statistical analysis. The survey results revealed that 74.2% of the respondents favored cleaning their hands more often due to the COCID-19 pandemic. In the same way, an overwhelming number of student respondents have become aware that wearing masks is crucial to prevent the spread, and 95.9% of student respondents have favored wearing masks if they decide to step outside of their house. Student respondents are more worried about the possibility that their family members will catch the COVID-19 virus than the concern of themselves catching the virus. The student respondents showed clear signs of worry and unpredictability due to the COVID-19 spread. More than have 37.6% have responded that they are in a constant state of worry during the lockdown. The paper states varied responses from the students on the anxiety levels and that they have been experiencing high anxiety levels during the lockdown. The measurement and correlation between emotional & preventive behavior can provide viable options to reduce the outbreak and further control it.
Бесплатно
Implementation of the principles of activation electromagnetotherapy in experimental oncology
Статья
Introduction. Identification of an important mechanism of homeostasis associated with the existence of a periodic system of general nonspecific adaptational reactions of the body (AR) [1-3] as well as the study of the conditions for the development of the anti-stress AR of high levels of reactivity as the most favorable AR for an organism, allowed determining the requirements for the parameters of external regulatory actions, acting factors and regimes of their application. As a result, the principles of activation therapy (AT) were formulated: it is a treatment technology aimed at the physiological mobilization of the mechanisms of general nonspecific (including antitumor) resistance of the body. Among the AT factors, one of the leading places is occupied by electromagnetic radiation (EMR), which has a wave nature, to which the CNS structures as well as regulatory and metabolic processes of lower levels are highly sensitive [1, 3].
Бесплатно
Статья научная
The aim of our research work was to study the level of sex steroids in blood, the tumor and the perifocal zone in rats of both sexes with Guerin’s carcinoma against the background of hypothyroidism. Materials and methods. The experiment was performed in 110 outbred rats of both sexes. Hypothyroidism was induced in animals for 30 days with Mercazolil medication, and then Guerin’s carcinoma was transplanted (the main group). The reference groups included animals with an independent growth of Guerin’s carcinoma and with independent hypothyroidism, as well as intact animals (the norm). On the 18th day of the tumor growth, the animals were sacrificed, and, using standard RIA kits, in the serum, the tumor homogenates and the perifocal zone, the levels of estradiol (E2), testosterone (T) and progesterone (P4) were determined. Results. In comparison with intact animals, hypothyroidism caused an increase in the blood content of E2 in animals of both sexes by 2.2-2.4 times and T by 1.4-16 times, and P4 by 1.7 times only in females, but recorded was a decrease therein in males by 2.4 times. The growth of Guerin’s carcinoma resulted in a 2.5-5.5-fold decrease in E2 in blood of the animals of both sexes, an increase in T by 2.1 times and P4 by 3 times in the females, but a decrease in T by 2.6 times without changing P4 in the males. In the main group, in the animals of both sexes, similarly to the processes in hypothyroidism, the level of E2 and P4 increased by 1.4-1.6 times, and in females also T by 4.4 times, compared with the intact animals. Conclusion. Hypothyroidism and the growth of Guerin’s carcinoma changed E2 in different directions in animals of both sexes the level of sex hormones in blood and shifted the steroid balance in the tumor and its perifocal zone. In the females of the main group, the saturation of the tumor with estrogens, androgens and progesterone decreased, while in the males, on the contrary, the concentration of steroids increased.
Бесплатно
