Статьи журнала - Cardiometry
Все статьи: 571
Статья научная
The current study was done to isolation and indentification of the Staphlococcus aureus isolates associated with polycystic ovarian syndrome patients and determine the molecular status for these patients and bacteria. The study included 155 clinical samples, which were collected from November 2022 to June 2023. The samples included blood samples - vaginal swabs. About 75 samples were collected from women with polycystic ovarian syndrome (PCOS) and 30 samples were collected from women with polycystic ovarian disease ( PCOD). They visit Imam Al-Sadiq Hospital and Babylon Teaching Hospital for Maternity and Children in Babylon Governorate. While 50samples were collected from women without polycystic ovaries as a healthy group. All samples were cultured on different media for full bacteriological identification . In addition, blood samples were taken in order to studying molecular status. The results of this study on the polymerase chain reaction revealed a number of genes related to Staphylococcus aureus isolates and some of its virulence factors, including genes (mec A, spa, luks). The study revealed the presence of the mec A gene in 5 out of 38 isolates. And by (13.15 %). While the spa gene was present in 9 out of 38 isolates, with a rate of (23.68 %). While the luks gene was present in 7 out of 38 isolates, with a rate of (18.42 %). while the study included the genes of sick people by detecting some genes, including the study of genetic polymorphisms of the gene for cytokine IL13 in patient samples.
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Association between vitamin d status and subclinical hypothyroidism
Статья научная
Aims and Objectives: The purpose of this study is to investigate the relation between Vitamin D levels and sub-clinical hypothyroidism and the effect of Vitamin D supplementation on treatment outcome. Design: A retrospective cohort file-based study. Method: In this study, the relation between Vitamin D level and subclinical hypothyroidism and the effect of Vitamin D supplementation on patients with subclinical hypothyroidism were evaluated where 30 patients were diagnosed with subclinical hypothyroidism followed up in Armed forces hospital southern region, KSA was included through electronic files revision. Results: The mean age was 41.6 +/- 12.4 years among the study group. Twenty-seven patients (90%) had their thyroid function test normalized after Vitamin D correction, while the rest had their TSH level improved from the baseline level. The presence of thyroid peroxidase antibodies (TPO) antibodies was found to be inversely related to TSH level after correction of Vitamin D level, and all patients who were negative for TPO 19 (100%) had their Thyroid Stimulating Hormone (TSH) level normalized after Vitamin D correction. In comparison, 3 (27.3%) of TPO-positive patients had subclinical hypothyroidism despite vitamin D correction. Conclusion: Vitamin D deficiency is inversely related to TSH, and TPO status and correction of Vitamin D deficiency in patients with subclinical hypothyroidism can normalize the thyroid function. Further studies are needed to establish the relationship between Vitamin D deficiency and subclinical hypothyroidism.
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Barriers to adoption of green buildings - a review
Статья научная
The global construction sector accounts for 13.2% of the world GDP. It contributes to the world’s economic growth engine and climate changes due to its high energy footprint. Sustainable buildings can reduce the adverse impacts of the construction industry, but their adoption is slow due to hindrances. The purpose of this paper is to extensively review the literature on barriers to green building adoption to date. Also, to highlight the overlapping and unique barriers specific to India compared to few prominent countries, provide solutions and recommendations for future research. The barriers were classified under Economic, Governmental, Organizational, and Social perception, Information, Technology, and material categories. Barriers unique to India and few others developing countries are an extension of project schedules, lack of research and developmental works, lack of public motivation, poor building code enforcement, high payback period, uncertain supply of green materials, improper implementation of policy framework, and performance of GBTs. The green building construction sector is fragmented around the world. Even green building definition is not the same globally, although the environmental aspect is the same. Similarly, there are unique and overlapping challenges in green building adoption globally. Buildings in usage perspectives can be classified into Residential and Non-residential. This study looks only at non-residential buildings due to their homogenous nature. There is a dearth of specific studies related to the adoption of green buildings in India. This study aims to fulfill India’s standing in the barriers to green building adoption concerning the developed and developing countries.
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Статья научная
Aims Basic criteria of finding the markers of the hemodynamic self-regulation mechanism on an ECG and a Rheogram are described herein. The basics of an analysis of the compensation mechanism responsible for the maintenance of the hemodynamic parameters within the norms are presented in this paper. Materials and A change in the form of an ECG phase segment reflects qualitatively the methods actual contraction performance of the respective cardiac muscle part involved. In case when the contraction of a cardiac muscle part is weak, an adjacent part undertakes the required compensation function in order to adjust the process. The causality analysis allows identifying the primary cause of a pathology which makes impossible to maintain the proper phase-related blood volumes within the norms. Results An evaluation of the hemodynamic self-regulation mechanism on the basis of the analysis of the compensation mechanism responsible for the maintenance of the hemodynamic parameters within the norms allows revealing the primary cause of the cardiovascular system pathology. Conclusion We offer an innovative methodology that is easy to use and very efficient, therefore, it can be widely applied in practice.
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Behavioral shift of generation X towards OTT during COVID’19 in India
Статья научная
Over-the-top (OTT) services such as Netflix, Prime Video, Disney+ Hotstar, Zee5, etc., have changed consumers’ content consumption behavior. Globalization and Digitalization have encouraged consumers to have limitless access to the Internet for information, leisure, entertainment, and social interconnectedness. The increase in the availability of high-speed Internet, the latest smartphones, and breakthroughs in technology have created great opportunities for the OTT sector, with people preferring to consume content on-the-go digitally rather than traditional media services, such as cable television. The Covid’19 pandemic has seen an increase in viewership’s and subscriptions towards these streaming platforms, with people of different age groups adapting to changing viewership trends. This study aims to understand Generation X’s behavioral shift (Age 41 to 55) towards OTT during Covid’19 in India. The literature review talks about the Generation X cohort of consumers, their behavioral habits, and attitudes towards technology. It also discusses the changing trends of online content consumption and how Covid’19 has created a spark in viewership’s towards India’s online media services. The research study aims to perform explanatory research to establish a relationship between the increase in consumption and subscriptions of OTT services in India by Generation X and the impact of Covid’19 on the same. Data will be collected from consumer’s age amongst 41 to 55 in India via survey questionnaires, and linear regression tests will be performed to test the hypotheses and establish a correlation between the dependent and independent variables.
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Now it is the time to consider directly the energy processes in the organism, which make an effect on the athletic performance, and not only thereon. In the organism, there is a coherent system of interactions between anaerobic and aerobic energy supply with the most active role of mitochondria.
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Статья научная
Objective: In this study, copper oxide nanoparticles are produced using the probiotic Saccharomyces boulardii in order to assess their biological activity. The biological method of producing nanoparticles is gaining popularity due to its benefits over chemical and physical ways of synthesis in terms of affordability and environmental friendliness. Methods: To biosynthesize CuO NPs, copper sulfate was introduced at a concentration to S. boulardii’s cellfree supernatant. Results: The color change of the reaction mixture from light to dark after 150 rpm incubation, as well as the color change and antibacterial behavior, were indicators of S. bularedii’s biosynthesis of CuO NPs. The characterization completed by UV-visible spectroscopy, Atomic force microscopy, Energy Dispersive Spectroscopy, Fourier Transform Infrared Spectroscopy, Scanning Electron Microscopy, and X-ray diffraction (AFM). The CuO NP absorption spectra in the reaction mixture’s UV visible spectroscopy were (537.93 nm). The XRD showed that CuO NPs’ crystal size was (14.65 nm). The SEM was provided; the shape was uniform and spherical, and the average size (16.03 nm). EDS was used to analyze the presence of elemental CuO NPs. The CuO NPs’ three-dimensional structure was seen by the AFM, and their average diameter was (41.11 nm). The FTIR spectrum reveals a variety of functional groups that are present at various locations. Gram positive and gram negative bacteria that were isolated from diabetic foot infections were multidrug resistant (MDR), and biosynthesized CuO NPs demonstrated antibacterial action against these bacteria (Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and Proteus mirabilis). In the form of biofilm using a microtiter plate.
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Статья научная
The aim is to evaluate the physiological parameters of the efficacy of cardiac mitochondria transplantation in male mice with chronic neurogenic pain and B16/F10 melanoma growth. Materials and methods. Male mice (n=37) of the C57BL/6 line were used in the research work. The animals covered experimental groups as follows: mice with chronic neurogenic pain (CNP) + B16/F10 melanoma (n=27); mice with CNB + B16/ F10 melanoma + mitochondrial therapy (MC therapy) (n=10). Mitochondria were isolated from the heart of an intact rat with the use of differential centrifugation. An introduction of mitochondria to mice was carried out daily intraperitoneally at a dose of 3.3 mg of protein for 3 weeks. Statistical analysis of the results is carried out with the Statistica 10.0 software. Results. On day 21 (week 3) of the experiment, macroscopically in the melanoma tissue in the group of animals with MC therapy, there were 2.5 times more necrosis cases than in the group without MC therapy. During the examination of the internal organs, no metastases were detected in the animals treated with MC therapy, while in 100% of the animals without MC therapy metastases were found in the lungs and in 95% of them in the spleen. In the animals received MC therapy, there was no damage to the heart muscle in 75% of the cases, while in the group of the animals without MC therapy, the presence of lesions in the form of bruises on the surface of the heart was macroscopically detected in 100% of the animals. Conclusion. Thus, intraperitoneal transplantation of intact heart mitochondria contributed to the prevention of myocardial infarction and metastases to internal organs in the C57BL/6 male mice with B16/F10 melanoma growing against the background of chronic neurogenic pain.
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Biological rhythms in the living cell: tunes of the life
Статья обзорная
Offered is an overview of the author's papers in exploring an interface between biological rhythms of energy, function and biosynthesis in a nerve cell of a crayfish stretch receptor. Parameters of mitochondrion aggregation rhythms integrally determine the energy metabolism in the cell. The level and the rhythms of aggregation of granular reticulum integrally reflect the regulation of biosynthesis in the body of the neuron cell. An influence of the functional activity on biosynthesis in the neuron soma and the influence of the pulse activity of the neuron are defined by rhythms of change in rates and density of flows of energy metabolism. An enhancement of the functional activity of a neuron corresponds to an increase in the rate of flow of energy produced, and an intensification of biosynthesis is linked with augmenting the energy flux density. The time lag in changing priorities in the energy regulation of the function and biosynthesis can explain variability of biological rhythm periods in a cell, the mechanism of the cell biological clock and an adaptation to the rhythms of the environment. Rhythms features of the function, biosynthesis and energetics are determined by a harmonization between the rhythms of sol-gel transitions in the cell compartments.
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Biophysical phenomena in blood flow system in the process of indirect arterial pressure measurement
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Статья научная
Objective: Saccharomyces boulardii, a probiotic, is used in the current study’s manufacture of zinc oxide nanoparticles with the aim of assessing their biological activity. Due to its advantages over the chemical and physical techniques of synthesis in terms of affordability and environmental friendliness, the biological way of creating nanoparticles is becoming increasingly relevant. Methods: Zinc acetate was added at a dose necessary to biosynthesize ZnO NPs from S. boulardii’s cellfree supernatant (1 mM). Results: An evidence that S. bularedii was responsible for the reaction mixture’s color change from light to dark after 150 rpm of incubation was the color change and antibacterial behavior. Atomic force microscopy, scanning electron microscopy, energy dispersive spectroscopy, ultraviolet visible spectroscopy, and X-ray diffraction (XRD) all contributed to the completion of the characterisation (AFM). The spectra of the ZnO NPs produced in the reaction mixture using UV-visible spectroscopy were (343.75 nm). The XRD showed that ZnO NPs’ crystal size was (13.31 nm). The SEM was provided; the shape was uniform and spherical, and the average size (24.61 nm). EDS was used to analyze the presence of elemental ZnO NPs. ZnO NPs’ three-dimensional structure was seen using AFM, and their average diameter was (62.89 nm). The FTIR spectrum reveals a variety of functional groups that are present at various locations. Gram positive and gram negative bacteria that were isolated from diabetic foot infections were multidrug resistant (MDR), and biosynthesized ZnO NPs demonstrated antibacterial action against these bacteria. (Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and Proteus mirabilis). All of the studied bacterial isolates showed the ability to produce biofilms in the form of nanoparticle-treated biofilms on microtiter plates.
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Статья научная
Breast health is extremely important for all women. However, the breast is another region of the human body that is susceptible to cancer. Breast cancer is becoming increasingly common these days, and it is now one of the leading causes of mortality globally. According to the World Health Organization, breast cancer is the most common disease among women worldwide, claiming the lives of hundreds of thousands of women each year and impacting nations at all stages of development. In fact, it is the most common cancer in women, with a significant incidence observed among those aged 30 to 50. The goal of the World Health Organization’s Worldwide Breast Cancer Initiative (GBCI) is to reduce global breast cancer mortality by 2.5 percent each year; As a result, 2.5 million breast cancer deaths will be avoided globally between 2020 and 2040. To achieve these goals, three pillars must be in place: health endorsement for early detection, suitable identification at the right time, and comprehensive breast cancer management. Because of advances in early detection and care, the incidence of women dying of breast cancer has decreased by 41% from 1989 to 2018. During that time, more than 403,000 breast cancer deaths were prevented.
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COVID-19 pandemic: impact and opportunities for education in India
Статья научная
The sudden breakout of COVID-19 has created a major crisis in almost every sector like Travel and Tourism, Entertainment, Sports, Corporates, Financials, Manufacturing, Education, and Service sectors. We cannot identify any sector which remained unaffected by the crisis. The magnitude of the impact may vary from sector to sector. The same happened to the Indian education system. It has faced a worldwide lockdown estimating to impact almost 320 million learners across the country. India has a robust education structure, with a huge chain of more than 1.4 million schools, 799 Universities, 39071 Colleges, and 11923 Stand Alone Institutions as per data available on the sixth report of ‘All India Survey on Higher Education on the web portal, are all affected by the pandemic situation. Our Indian education system was badly impacted due to pandemics, mostly based on traditional or classroom teaching. Though most of the school and colleges, for the benefit of students, had opted for online teaching, yet some of the low income private and government teaching institutes and students from a remote location could not opt to online teaching due to the unavailability of the internet, Laptop, Desktop or Smartphones persistent with a survey by EY-Parthenon.
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Статья научная
The aim of this research work is to study the cAMP level in the cardiac mitochondria and serum in the C57BL/6 strain mice of both genders under the independent melanoma B16/F10 growth versus the melanoma B16/F10 growth linked to chronic neurogenic pain (CNP). Materials and methods. Mice of strain C57BL/6 (n=336) have been grouped as follows: the intact group of the mice (♂n=21; ♀n=21), the reference group (♂n=21; ♀n=21) with the reproduced CNP model, the comparison group (♂n=63; ♀n=63) to include the mice with melanoma B16/F10, and the main test group (♂n=63; ♀n=63) to cover the mice with the melanoma growth against the CNP background. Upon expiration of 1 week, 2 and 3 weeks of the melanoma growth, in the animals of the above experimental groups the cardiac mitochondria have been isolated with the centrifugation using high-performance refrigerated centrifuge Avanti J-E, BECMAN COULTER, USA. With ELISA Kit (RayBio USA) we have determined cAMP concentrations in serum and in the cardiac mitochondria. Results. CNP has induced a decrease in the cAMP level in the cardiac mitochondria by a factor of 3,6 in the female mice only. In the animals of the comparison group the cAMP level in the heart has been increasing beginning with week 2 of the tumor growth on average by a factor of 4, while in the main test group starting from week 1 of the tumor growth it has been recorded 2-4 times higher and was depleted by the end of the experiment. As to the cAMP concentration in serum, the dynamics thereof has not been found to be in correlation with the cardiac mitochondrial data, and its concentration decrease has been recorded both in the females and the males. Conclusion. So, the changes in the cAMP concentration in the cardiac mitochondria demonstrate their gender-specific feature; the female mice as against the males have responded to an independent impact produced by CNP. As to the main test group, CNP has stimulated an increase in the cAMP level in the cardiac mitochondria 1 week earlier than it is the case with the comparison group, and it has resulted in the full cAMP depletion by the 3rd week of the experiment.
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Отчет
The aim of the study was to evaluate the significance of cardioeigenoscopy method for the prognosis of risks of fatal arrhythmia (the primary and secondary VF) progression in AMI individuals.The study was performed with the use of the PC-assisted hemodynamic analyzer Cardiocode. The cardio-eigenoscopy was developed as a methodology that is capable of presenting all ECG changes in the basis of eigenvectors of a covariance matrix of ECG amplitudes and providing an analysis of a spectrum of eigenvalues. The ECG analysis software is implemented as a real-time monitoring of a set of parameters that makes possible to evaluate the therapy effectiveness. The cardio-eigenoscopy method is capable of assessing the risk of progression of fatal arrhythmia events in MI patients. The major markers of the possible progression of fatal arrhythmia were identified. The cardioeigenoscopy provided the maximum expressibility of an ECG curve at any specified EVE values.
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Cardio-oculometric (cardio-oculographic) detection of functional states in a human individual
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The cardio-oculometric detection (COD) is an integrated method aimed at studying personal preferences, individual traits and current functional states of a human individual. The method is based on the use of some cardiac markers and parameters of oculomotor activity in response to specially selected visual and audial stimuli.
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Cardio-oсulometric indicators of psychophysiological readiness of students to examinations
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The article presents some experimental results demonstrating the suitability of using the psycho-physiological reactions recorded with the Cardiocode device and the Barrier-14 polygraph to specially selected visual stimuli in order to assess the degree of authenticity of vital goals chosen by a person as key benchmarks in the implementation of the desired future.
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Статья научная
The aim is to conduct a cardiometric assessment of formation of acute and late toxic disorders in experimental animals with Guerin's carcinoma during carboplatin chemotherapy against the background of L-carnitine medication
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